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Clinical utility of low-density lipoprotein particle measurement in management of cardiovascular disease: a case report

Authors Dall T, Pourfarzib

Published 28 April 2011 Volume 2011:2 Pages 57—62

DOI https://doi.org/10.2147/RRCC.S17803

Review by Single-blind

Peer reviewer comments 2


Tara L Dall1, Ray Pourfarzib2
1Advanced Lipidology, Delafield, WI, USA; 2LipoScience Inc, Raleigh, NC, USA

Abstract: Despite adequate screening and low-density lipoprotein cholesterol (LDL-C)-lowering therapy, it has been recognized that many patients with low or moderate LDL-C levels experience cardiovascular events. Furthermore, many patients with cardiovascular disease and relatively normal levels of LDL-C have increased levels of low-density lipoprotein particles (LDL-P). The purpose of this case report is to illustrate the importance of LDL-P in the surprising presentation of vascular disease in a woman who had a high concentration of high-density lipoprotein cholesterol (HDL-C). By utilizing lipoprotein information, patients can be appropriately selected to receive suitable medication, leading to better health outcomes.

Keywords: lipoprotein particle concentration, premature coronary artery disease, lipid profile, combination therapy, vitamin D deficiency

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