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Clinical Trial of Low Irritative Skin Care Cosmetics in Japanese Subjects with Dry Skin

Authors Tanaka K, Nagasawa T, Nomura Y, Kubota Y, Miyake A, Kawamura K, Yamaguchi Y

Received 18 August 2020

Accepted for publication 22 September 2020

Published 2 November 2020 Volume 2020:13 Pages 805—814

DOI https://doi.org/10.2147/CCID.S277569

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Jeffrey Weinberg


Kazunori Tanaka,1 Teruaki Nagasawa,1 Yuko Nomura,2 Yoshiki Kubota,1 Akihiko Miyake,1 Kimio Kawamura,1 Yoko Yamaguchi1

1Pharmaceutical Products Research and Development Section, NANOEGG® Research Laboratories, Inc, Kawasaki, Kanagawa, Japan; 2Nomura Dermatology Clinic, Yokohama, Kanagawa, Japan

Correspondence: Yoko Yamaguchi
Pharmaceutical Products Research and Development Section, NANOEGG® Research Laboratories, Inc., Innovation Center of NanoMedicine 4F, 3-25-14 Tono-Machi, Kawasaki-Ku, Kawasaki, Kanagawa 210-0821, Japan
Tel +81 44 400 1155
Fax +81 3 6685 3127
Email rdm@nanoegg.co.jp

Purpose: To evaluate whether MediQOL, which was developed as a care cosmetic for sensitive skin, causes a change in skin condition for subjects with dry skin requiring moisture retention.
Subjects and Methods: This study includes 20 Japanese subjects with dry skin who required moisture retention, as identified by a dermatologist. The subjects used the novel MediQOL products twice a day for four consecutive weeks. A skin evaluation was performed by a dermatologist, and each subject completed a questionnaire prior to the study period and after two and four weeks of MediQOL use.
Results: After four weeks of MediQOL use, alleviation of skin dryness, redness, and itchiness was observed in the subjects. The water/oil content of the skin also improved during the study period.
Conclusion: Four weeks of MediQOL use resulted in the alleviation of skin dryness, redness, and itchiness and balanced the water/oil content of the skin. MediQOL is expected to be effective in improving the condition of various skin types, including oily, mixed, and sensitive skin as well as dry skin.

Keywords: skin care, dryness, erythema, humidity retention, quality of life

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