Back to Archived Journals » Journal of Neurorestoratology » Volume 3

Clinical neurorestorative progress in Alzheimer’s disease

Authors Qiao L, Huang H, Muresanu D

Received 30 September 2014

Accepted for publication 31 October 2014

Published 15 December 2014 Volume 2015:3 Pages 1—9

DOI https://doi.org/10.2147/JN.S74143

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Hari Shanker Sharma


Liyan Qiao,1 Hongyun Huang,2,3 Dafin F Muresanu4,5

1Department of Neurology, Tsinghua University Yuquan Hospital, 2Beijing Rehabilitation Hospital of Capital Medical University, 3Beijing Hongtianji Neuroscience Academy, Beijing, People's Republic of China; 4Department of Clinical Neurosciences, Iuliu Hatieganu University of Medicine and Pharmacy, 5RoNeuro Institute for Neurological Research and Diagnosis, Cluj-Napoca, Romania

Abstract: Alzheimer’s disease (AD) is the most prevalent type of dementia, and its neuropathology is characterized by the deposition of insoluble β-amyloid peptides and intracellular neurofibrillary tangles and the loss of diverse neurons. Although much is known about the neurobiology of AD, few treatments are available to arrest or slow the illness. There is an urgent need for novel therapeutic approaches for AD. We reviewed the recent improvements in the neurorastorlogy strategies for AD, including medicine, bioengineering and neuromodulation and clinical cell therapy. We emphasized that cell therapy may be an promising treatment for AD.

Keywords: Alzheimer's disease, neurorastorlogy, cell therapy, medicine

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