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Chronic, Recurrent Bacterial Endophthalmitis Caused by Achromobacter xylosoxidans: Clinical Features and Management

Authors Lazzarini TA, Al-khersan H, Patel NA, Yannuzzi NA, Martinez JD, Altamirano D, Torres LK, Miller D, Batlle JF, Amescua G, Flynn HW Jr

Received 25 April 2020

Accepted for publication 8 June 2020

Published 9 July 2020 Volume 2020:13 Pages 265—269


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Thomas A Lazzarini,1 Hasenin Al-khersan,1 Nimesh A Patel,1 Nicolas A Yannuzzi,1 Jaime D Martinez,1 Diego Altamirano,1 Lizt K Torres,2 Darlene Miller,1 Juan F Batlle,1,2 Guillermo Amescua,1 Harry W Flynn Jr1

1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA; 2Laser Center, Santo Domingo, Dominican Republic

Correspondence: Thomas A Lazzarini
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 900 NW 17th Street, Miami, FL 33136, USA
Tel +1 305 326-6118
Fax +1 305 326-6417

Abstract: A 79-year-old man presented to a tertiary referral center from the Dominican Republic with an opaque corneal graft and a diagnosis of chronic, recurrent culture-positive Achromobacter xylosoxidans endophthalmitis of the left eye. The patient had a history of penetrating keratoplasty for Fuchs’ dystrophy and had undergone multiple intraocular surgeries including pars plana vitrectomy and anterior chamber wash out for the diagnosis and management of chronic endophthalmitis. After being referred, the patient underwent a third PKP, removal of his intraocular lens (IOL), capsulectomy, and injection of intravitreal antibiotics. All surgical specimens demonstrated the growth of A. xylosoxidans. Five months after surgery, the graft remained clear without evidence of infection and best-corrected visual acuity was 20/350.

Keywords: endophthalmitis, Achromobacter xylosoxidans, ophthalmlology, postoperative endophthalmitis, ophthalmic infection

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