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Childhood-onset growth hormone deficiency and the transition to adulthood: current perspective

Authors Ahmid M, Ahmed SF, Shaikh MG

Received 28 March 2018

Accepted for publication 19 August 2018

Published 23 November 2018 Volume 2018:14 Pages 2283—2291

DOI https://doi.org/10.2147/TCRM.S136576

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 5

Editor who approved publication: Professor Garry Walsh


M Ahmid, SF Ahmed, MG Shaikh

Development Endocrinology Research Group, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK

Abstract: Childhood-onset growth hormone deficiency (CO-GHD) is an endocrine condition associated with a broad range of health issues from childhood through to adulthood, which requires particular attention during the transition period from adolescence to young adulthood. There is uncertainty in the clinical practice of the management of CO-GHD during transition regarding the clinical assessment and management of individual patients during and after transition to obtain optimal follow-up and improved health outcomes. Despite the availability of clinical guidelines providing the framework for transition of young adults with CO-GHD, there remains substantial variation in approaching transitional care among pediatric and adult services. A well-structured and coordinated transitional plan with clear communication and direct collaboration between pediatric and adult health care to ensure optimal management of adolescents with CO-GHD during transition is needed.

Keywords: growth hormone deficiency, childhood-onset, transition, adolescents

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