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Central serous chorioretinopathy following ingestion of sildenafil citrate

Authors Mohammadpour M, Khodaparast M, Khorrami-Nejad M

Received 2 April 2019

Accepted for publication 14 June 2019

Published 8 July 2019 Volume 2019:11 Pages 73—75

DOI https://doi.org/10.2147/OPTO.S210877

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Mr Simon Berry


Mehrdad Mohammadpour,1 Mehdi Khodaparast,1 Masoud Khorrami-Nejad1,2

1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Introduction: We report a case of a 35-year-old man who presented with headache followed by decreased vision, metamorphopsia, and altered color perception in his left eye, after repeated intake of sildenafil citrate (four times; 100 mg) in a limited period (3 days).
Methods: On the first ocular examination, best-corrected distance visual acuity (CDVA) was 20/80 in his left eye and 20/20 in his right eye. On fundus examination, loss of foveal reflex and serous retinal detachment in the foveal region were detected. Fluorescein angiography of the left eye was compatible with a leakage area with determined borders. The patient was advised to stop sildenafil intake.
Results: After 4 weeks, CDVA increased to 20/25, and the fundus examination revealed significant improvement of the macular edema. Optical coherence tomography showed increased foveal thickness to 350 μm.
Conclusion: Advising patients with central serous chorioretinopathy to stop sildenafil intake should be considered.

Keywords: central serous chorioretinopathy, sildenafil citrate, serous retinal detachment

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