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Bilateral acute closed-angle glaucoma associated with the discontinuation of escitalopram: a case report

Authors AlQuorain S, Alfaraj S, Alshahrani M

Received 1 March 2016

Accepted for publication 18 May 2016

Published 8 September 2016 Volume 2016:8 Pages 61—65

DOI https://doi.org/10.2147/OAEM.S107551

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Hans-Christoph Pape


Sara AlQuorain,1 Sukayna Alfaraj,2 Mohammed Alshahrani2

1Department of ENT, 2Department of Emergency Medicine, King Fahad Hospital of the University, University of Dammam, Dammam, Saudi Arabia

Abstract: A 45-year-old woman presented to the Emergency Department complaining of severe headache for 3 hours duration associated with bilateral blurred vision, photophobia, and one attack of vomiting. Her clinical examination revealed normal vital signs and decrease in visual acuity with hazy cornea bilaterally. There were no signs of increased intracranial pressure and no neck rigidity or meningeal signs. The patient was diagnosed with bilateral acute closed angle glaucoma (AACG) with intraocular pressure of 60 mmHg in both eyes. She was using escitalopram for the treatment of depression, which was the only known risk factor for her condition. Standard treatment for AACG was provided. It included topical β-blocker, α agonists, and acetazolamide. This was followed by bilateral peripheral iridotomy. Follow-up intraocular pressure measurement revealed a value of 5 mmHg after 24 hours, indicating complete recovery. To the best of our knowledge, this is the first case to describe AACG after stopping the medication. It is highly important that clinicians be aware of this risk factor for AACG and have high index of suspicion in such patients with vision-threatening condition even after discontinuing the medication, because the risk persists for some time.

Keywords: acute closed angle glaucoma, escitalopram, intraocular pressure

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