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Beyond photoaging: additional factors involved in the process of skin aging

Authors Addor FAS

Received 16 June 2018

Accepted for publication 18 July 2018

Published 20 September 2018 Volume 2018:11 Pages 437—443


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Jeffrey Weinberg

Flavia Alvim Sant’Anna Addor

MEDCIN Research, Private Clinical Research Center, Osasco, São Paulo, Brazil

Abstract: Studies assessing the impact of extrinsic factors on skin aging have increased during the last with the increase in life expectancy. Although most of the studies are about the sun radiation impact, many factors should be considered in elderly people, beyond environmental conditions. Lifestyle factors, like diet, sleeping, smoking, should be analyzed carefully, as common age-related conditions (menopause, diabetes, pulmonary diseases, etc.). All these factors could accelerate the natural decline of skin structure and functions, possibly affecting the responses to treatments and drugs. This review demonstrates that growing evidence regarding environmental factors that are associated with lifestyle and comorbidities deserve greater attention from researchers and dermatologists and may require new approaches in the management of skin aging.

Keywords: skin aging, oxidative stress, photoaging, pollution, diabetes mellitus, nutrition, glycation, age-related diseases, sleep disorders, chronic stress

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