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Average annual cost of Parkinson’s disease in São Paulo, Brazil, with a focus on disease-related motor symptoms

Authors Bovolenta TM, Azevedo Silva SM, Saba RA, Borges V, Ferraz HB, Felicio AC

Received 18 September 2017

Accepted for publication 3 November 2017

Published 14 December 2017 Volume 2017:12 Pages 2095—2108

DOI https://doi.org/10.2147/CIA.S151919

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 2

Editor who approved publication: Dr Richard Walker


Tânia M Bovolenta,1 Sônia Maria Cesar de Azevedo Silva,2 Roberta Arb Saba,3 Vanderci Borges,2 Henrique Ballalai Ferraz,2 Andre C Felicio1

1Hospital Israelita Albert Einstein, São Paulo, 2Neurology Department, Federal University of São Paulo, UNIFESP, São Paulo, 3Neurology Department, Federal University of São Paulo, UNIFESP, São Paulo, Brazil

Background: Although Parkinson’s disease is the second most prevalent neurodegenerative disease worldwide, its cost in Brazil – South America’s largest country – is unknown.
Objective: The goal of this study was to calculate the average annual cost of Parkinson’s disease in the city of São Paulo (Brazil), with a focus on disease-related motor symptoms.
Subjects and methods: This was a retrospective, cross-sectional analysis using a bottom-up approach (ie, from the society’s perspective). Patients (N=260) at two tertiary public health centers, who were residents of the São Paulo metropolitan area, completed standardized questionnaires regarding their disease-related expenses. We used simple and multiple generalized linear models to assess the correlations between total cost and patient-related, as well as disease-related variables.
Results: The total average annual cost of Parkinson’s disease was estimated at US$5,853.50 per person, including US$3,172.00 in direct costs (medical and nonmedical) and US$2,681.50 in indirect costs. Costs were directly correlated with disease severity (including the degree of motor symptoms), patients’ age, and time since disease onset.
Conclusion: In this study, we determined the cost of Parkinson’s disease in Brazil and observed that disease-related motor symptoms are a significant component of the costs incurred on the public health system, patients, and society in general.

Keywords: Parkinson’s disease, health economics, cost of illness, health evaluation, cost analysis

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