First-in-Human Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of BIIB091, an Oral BTK Inhibitor, in Healthy Adult Participants

Tsai HH, Gu Y, Riester K, Chu SS, Bame E, Arefayene M, Kam JLYL, Coppell A, Hanna J, Hopkins BT, Scaramozza M

Drug Design, Development and Therapy 2026, 20:571780

Published Date: 14 April 2026