Back to Browse Journals » Vascular Health and Risk Management » Volume 9

Atrial fibrillation and thromboprophylaxis in heart failure: the need for patient-centered approaches to address adherence

Authors Ferguson C, Inglis SC, Newton PJ, Middleton S, Macdonald PS, Davidson PM

Received 25 October 2012

Accepted for publication 10 December 2012

Published 17 January 2013 Volume 2013:9 Pages 3—11


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Caleb Ferguson,1 Sally C Inglis,1 Phillip J Newton,1 Sandy Middleton,2,3 Peter S Macdonald,3,4 Patricia M Davidson1,3

1Center for Cardiovascular and Chronic Care, University of Technology, 2National Center for Clinical Outcomes Research (NaCCOR), Australian Catholic University, 3St Vincent's Hospital, Darlinghurst, Sydney, Australia; 4Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia

Abstract: Atrial fibrillation is a common arrhythmia in heart failure and a risk factor for stroke. Risk assessment tools can assist clinicians with decision making in the allocation of thromboprophylaxis. This review provides an overview of current validated risk assessment tools for atrial fibrillation and emphasizes the importance of tailoring individual risk and the importance of weighing the benefits of treatment. Further, this review provides details of innovative and patient-centered methods for ensuring optimal adherence to prescribed therapy. Prior to initiating oral anticoagulant therapy, a comprehensive risk assessment should include evaluation of associated cardiogeriatric conditions, potential for adherence to prescribed therapy, frailty, and functional and cognitive ability.

Keywords: stroke risk, heart failure, atrial fibrillation, anticoagulation, risk stratification, medication adherence

Download Article [PDF] View Full Text [HTML] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at:

Readers of this article also read:

Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function

Sakai T, Sato B, Hara K, Hara Y, Naritomi Y, Koyanagi S, Hara H, Nagao T, Ishibashi T

Vascular Health and Risk Management 2014, 10:591-597

Published Date: 17 October 2014

Thoracoabdominal aortic aneurysm repair: current endovascular perspectives

Orr N, Minion D, Bobadilla JL

Vascular Health and Risk Management 2014, 10:493-505

Published Date: 19 August 2014

Vitamin E tocotrienol supplementation improves lipid profiles in chronic hemodialysis patients

Daud ZAM, Tubie B, Sheyman M, Osia R, Adams J, Tubie S, Khosla P

Vascular Health and Risk Management 2013, 9:747-761

Published Date: 28 November 2013

Efficacy of vildagliptin in combination with insulin in patients with type 2 diabetes and severe renal impairment

Lukashevich V, Schweizer A, Foley JE, Dickinson S, Groop PH, Kothny W

Vascular Health and Risk Management 2013, 9:21-28

Published Date: 23 January 2013

Low body temperature associated with severe ischemic stroke within 6 hours of onset: The Bergen NORSTROKE Study

Kvistad CE, Thomassen L, Waje-Andreassen U, Naess H

Vascular Health and Risk Management 2012, 8:333-338

Published Date: 1 June 2012

RGD peptide-mediated chitosan-based polymeric micelles targeting delivery for integrin-overexpressing tumor cells

Cai LL, Liu P, Li X, Huang X, Ye YQ, Chen FY, Yuan H, Hu FQ, Du YZ

International Journal of Nanomedicine 2011, 6:3499-3508

Published Date: 21 December 2011

Sexual dysfunction in patients with schizophrenia treated with conventional antipsychotics or risperidone

Hong Liu-Seifert, Bruce J Kinon, Christopher J Tennant, Jennifer Sniadecki, Jan Volavka

Neuropsychiatric Disease and Treatment 2009, 5:47-54

Published Date: 22 January 2009

A review of ramelteon in the treatment of sleep disorders

David N Neubauer

Neuropsychiatric Disease and Treatment 2008, 4:69-79

Published Date: 8 February 2008

Severe supraaortal atherosclerotic disease resembling Takayasu’s Arteritis

Bernhard Kis, Thomas Liebig, Peter Berlit

Vascular Health and Risk Management 2007, 3:351-354

Published Date: 15 July 2007