Risk factors of hospitalization and readmission of patients with COPD exacerbation – systematic review
Authors Katayoon Bahadori, J Mark FitzGerald
Published 15 October 2007 Volume 2007:2(3) Pages 241—251
Katayoon Bahadori1, J Mark FitzGerald1, 2
1Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada 2The Lung Centre, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada
Background: Chronic obstructive lung disease (COPD) exacerbations are a significant cause of morbidity and mortality. Data regarding factors which causes or prevents exacerbations is very limited. The aim of this systematic review is to summarize the results from available studies to identify potential risk factors for hospital admission and/or re-admission among patients experiencing COPD exacerbations.
Methods: We undertook a systematic review of the literature. Potential studies were identified by searching the electronic databases: PubMed, EMBASE, BIOSIS, CINAHL, PsycINFO, Cochrane library, reference lists in trial reports, and other relevant articles.
Results: Seventeen articles that met the predefined inclusion criteria were identified. Heterogeneity of study designs, risk factors and outcomes restrict the result to only a systematic review and precluded a formal meta-analysis. In this review, three predictive factors: previous hospital admission, dyspnea and oral corticosteroids were all found to be significant risk factors of readmissions and variables including using long term oxygen therapy, having low health status or poor health related quality of life and not having routine physical activity were all associated with an increased risk of both admission and readmission to hospital.
Conclusions: There are a number of potential modifiable factors that are independently associated with a higher risk of COPD exacerbation requiring admission/readmission to the hospital. Identifying these factors and the development of targeted interventions could potentially reduce the number and severity of such exacerbations.
Keywords: COPD exacerbations, hospitalizations, risk of admission, readmission
Readers of this article also read:
Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry
Santos-Martinez MJ, Tomaszewski KA, Medina C, Bazou D, Gilmer JF, Radomski MW
Published Date: 13 August 2015
Travoprost with sofZia® preservative system lowered intraocular pressure of Japanese normal tension glaucoma with minimal side effects
Mizoue S, Nakano T, Fuse N, Iwase A, Matsumoto S, Yoshikawa K, IOP CHANGE Study Group
Published Date: 3 February 2014
Shoughy SS, Tabbara KF
Published Date: 24 January 2014
Postural stability and quality of life after guided and self-training among older adults residing in an institutional setting
Tuunainen E, Rasku J, Jäntti P, Moisio-Vilenius P, Mäkinen E, Toppila E, Pyykkö I
Published Date: 16 September 2013
Conversano F, Soloperto G, Greco A, Ragusa A, Casciaro E, Chiriacò F, Demitri C, Gigli G, Maffezzoli A, Casciaro S
Published Date: 9 August 2012
Haniu H, Tsukahara T, Matsuda Y, Usui Y, Aoki K, Shimizu M, Ogihara N, Hara K, Takanashi S, Okamoto M, Ishigaki N, Nakamura K, Kato H, Saito N
Published Date: 4 November 2011
Cardiovascular application of polyhedral oligomeric silsesquioxane nanomaterials: a glimpse into prospective horizons
Ghanbari H, de Mel A, Seifalian AM
Published Date: 13 April 2011
Ruiying Zhao, Enrique Fuentes-Mattei, Guermarie Velazquez-Torres, et al
Published Date: 26 January 2011
Cindy Hutnik, Mohammad H Mohammad-Shahi
Published Date: 6 December 2010