Back to Browse Journals » Vascular Health and Risk Management » Volume 4 » Issue 5

Habitual coffee consumption and blood pressure: An epidemiological perspective

Authors Johanna M Geleijnse

Published 10 October 2008 Volume 2008:4(5) Pages 963—970


Review by Single-blind

Peer reviewer comments 3

Johanna M Geleijnse

Division of Human Nutrition, Wageningen University, The Netherlands

Abstract: This paper summarizes the current epidemiological evidence on coffee consumption in relation to blood pressure (BP) and risk of hypertension. Data from crosssectional studies suggest an inverse linear or U-shaped association of habitual coffee use with BP in different populations. Prospective studies suggest a protective effect of high coffee intake (4 or more cups per day) against hypertension, mainly in women. Furthermore, the risk of hypertension may be lower in coffee abstainers. Randomized controlled trials, which are mostly of short duration (1–12 weeks), have shown that coffee intake around 5 cups per day causes a small elevation in BP (∼2/1 mmHg) when compared to abstinence or use of decaffeinated coffee. With regard to underlying biological mechanisms, most research has been devoted to BP-raising effects of caffeine. However, there are many other substances in coffee, such as polyphenols, soluble fi bre and potassium, which could exert a beneficial effect in the cardiovascular system. Although the precise nature of the relation between coffee and BP is still unclear, most evidence suggests that regular intake of caffeinated coffee does not increase the risk of hypertension.

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF] 


Readers of this article also read:

Passive tumor targeting and imaging by using mercaptosuccinic acid-coated near-infrared quantum dots

Lin G, Wang X, Yin F, Yong KT

International Journal of Nanomedicine 2015, 10:335-345

Published Date: 6 January 2015

In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery

Banizs AB, Huang T, Dryden K, Berr SS, Stone JR, Nakamoto RK, Shi W, He J

International Journal of Nanomedicine 2014, 9:4223-4230

Published Date: 3 September 2014

Nanotherapeutics in the EU: an overview on current state and future directions

Hafner A, Lovrić J, Perina Lakoš G, Pepić I

International Journal of Nanomedicine 2014, 9:1005-1023

Published Date: 19 February 2014

Selective laser sintering fabrication of nano-hydroxyapatite/poly-ε-caprolactone scaffolds for bone tissue engineering applications

Xia Y, Zhou PY, Cheng XS, Xie Y, Liang C, Li C, Xu SG

International Journal of Nanomedicine 2013, 8:4197-4213

Published Date: 1 November 2013

A tissue-engineered subcutaneous pancreatic cancer model for antitumor drug evaluation

He Q, Wang X, Zhang X, Han H, Han B, Xu J, Tang K, Fu Z, Yin H

International Journal of Nanomedicine 2013, 8:1167-1176

Published Date: 19 March 2013

Induction of oxidative stress, DNA damage, and apoptosis in a malignant human skin melanoma cell line after exposure to zinc oxide nanoparticles

Alarifi S, Ali D, Alkahtani S, Verma A, Ahamed M, Ahmed M, Alhadlaq HA

International Journal of Nanomedicine 2013, 8:983-993

Published Date: 7 March 2013

Reversing chemoresistance of malignant glioma stem cells using gold nanoparticles

Orza A, Soriţău O, Tomuleasa C, Olenic L, Florea A, Pana O, Bratu I, Pall E, Florian S, Casciano D, Biris AS

International Journal of Nanomedicine 2013, 8:689-702

Published Date: 1 March 2013

A comparative study of the prevalence of hyperkalemia with the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers

Seyed Ali Sadjadi, James I McMillan, Navin Jaipaul, Patricia Blakely, et al.

Therapeutics and Clinical Risk Management 2009, 5:547-552

Published Date: 10 July 2009

Inhaled insulin for controlling blood glucose in patients with diabetes

Bernard L Silverman, Christopher J Barnes, Barbara N Campaigne, Douglas B Muchmore

Vascular Health and Risk Management 2007, 3:947-958

Published Date: 15 January 2008