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Agreement of swept-source and spectral-domain optical coherence-tomography retinal thickness measurements in neovascular age-related macular degeneration

Authors Hanumunthadu D, Ilginis T, Balaggan KS, Patel PJ

Received 7 August 2017

Accepted for publication 19 October 2017

Published 29 November 2017 Volume 2017:11 Pages 2121—2123

DOI https://doi.org/10.2147/OPTH.S148505

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Daren Hanumunthadu,1 Tomas Ilginis,1 Kamaljit S Balaggan,1,2 Praveen J Patel1

On behalf of the DOCS team

1NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and University College London Institute of Ophthalmology, London, 2Wolverhampton and Midland Counties Eye Infirmary, Wolverhampton, UK

Changes in macular thickness measurements in neovascular age-related macular degeneration (nAMD) are thought to reflect disease activity, and can be used to guide treatment with antiangiogenic agents.1 Both spectral-domain optical coherence tomography (SD-OCT) and the more recently introduced swept-source optical coherence tomography (SS-OCT) have onboard segmentation algorithms that deliver automated retinal thickness measurements. Agreement between OCT derived macular thickness measurements is critical for monitoring of patients if these modalities are to be used interchangeably. This prospective cross-sectional study sought to determine the limits of agreement between SD-OCT (Spectralis; Heidelberg Engineering) and SS-OCT (DRI OCT-1 Atlantis; Topcon Medical Systems) in patients with nAMD.

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