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Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa

Authors Nakamura Y, Kamimura M, Koiwai H, Kato H

Received 19 December 2017

Accepted for publication 9 February 2018

Published 18 May 2018 Volume 2018:14 Pages 945—948

DOI https://doi.org/10.2147/TCRM.S160280

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Justinn Cochran

Peer reviewer comments 2

Editor who approved publication: Professor Garry Walsh


Yukio Nakamura,1,2 Mikio Kamimura,3 Hidefumi Koiwai,4 Hiroyuki Kato1

1Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan; 2Department of Orthopedic Surgery, Showa-Inan General Hospital, Komagane, Japan; 3Center of Osteoporosis and Spinal Disorders, Kamimura Orthopedic Clinic, Matsumoto, Japan; 4Koiwai Orthopedic Clinic, Komoro, Japan

Abstract: Low bone mineral density (BMD) is one of the most frequent complications of anorexia nervosa (AN). We report the clinical outcomes of a female patient with severe AN, whose chest had become deformed due to thoracic fracture. Lumbar BMD was 0.358 g/cm2 (T-score = −6.3), and total hip BMD was 0.411 g/cm2 (T-score = −4.4). Active vitamin D increased these parameters by 81.0% and 57.4%, respectively, but a drop in her nutrition status afterward resulted in a sharp decrease in BMD values. These findings suggest that adequate nutrient intake is essential for effective osteoporosis treatment in patients with AN.

Keywords: anorexia nervosa, bone mineral density, daily teriparatide, osteoporosis

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