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Acute necrotizing encephalopathy in an adult with influenza A infection

Authors Ochi N, Takahashi K, Yamane H, Takigawa N

Received 17 December 2017

Accepted for publication 1 March 2018

Published 20 April 2018 Volume 2018:14 Pages 753—756

DOI https://doi.org/10.2147/TCRM.S160111

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Professor Garry Walsh


Nobuaki Ochi,1 Kento Takahashi,2 Hiromichi Yamane,1 Nagio Takigawa1

1Department of General Internal Medicine 4, Kawasaki Medical School, Okayama, Japan; 2Clinical Education and Training Center, Kawasaki General Medical Center, Kawasaki Medical School, Okayama, Japan

Abstract: Acute necrotizing encephalopathy following influenza infection is a rapidly progressing disease with high morbidity. Although the neurological disorder is sometimes reported in children, it is very rare in adults. We herein describe an adult with acute necrotizing encephalopathy captured on a series of brain magnetic resonance images. A 55-year-old man had fever and impaired consciousness. He was diagnosed with influenza A (H1N1). Brain magnetic resonance imaging revealed symmetrical lesions in the cerebellum and basal nucleus, showing typical acute necrotizing encephalopathy. Physicians should know that influenza-associated acute necrotizing encephalopathy can occur even in middle-aged adults.

Keywords: acute necrotizing encephalopathy, influenza A, magnetic resonance imaging, adult

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