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A practical method for the detection of freezing of gait in patients with Parkinson’s disease

Authors Kwon Y, Park SH, Kim JW, Ho Y, Jeon HM, Bang MJ, Jung GI, Lee SM, Eom GM, Koh SB, Lee JW, Jeon HS

Received 21 June 2014

Accepted for publication 14 August 2014

Published 8 October 2014 Volume 2014:9 Pages 1709—1719

DOI https://doi.org/10.2147/CIA.S69773

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Dr Richard Walker

Yuri Kwon,1 Sang Hoon Park,1 Ji-Won Kim,1 Yeji Ho,1 Hyeong-Min Jeon,1 Min-Jung Bang,1 Gu-In Jung,1 Seon-Min Lee,3 Gwang-Moon Eom,1,2 Seong-Beom Koh,3 Jeong-Whan Lee,1,2 Heung Seok Jeon4

1Biomedical Engineering, 2Research Institute of Biomedical Engineering, Konkuk University, Chungju, Korea; 3Department of Neurology, Korea University College of Medicine, Seoul, Korea; 4Department of Computer Engineering, Konkuk University, Chungju, Korea

Purpose: Freezing of gait (FOG), increasing the fall risk and limiting the quality of life, is common at the advanced stage of Parkinson’s disease, typically in old ages. A simple and unobtrusive FOG detection system with a small calculation load would make a fast presentation of on-demand cueing possible. The purpose of this study was to find a practical FOG detection system.
Patients and methods: A sole-mounted sensor system was developed for an unobtrusive measurement of acceleration during gait. Twenty patients with Parkinson’s disease participated in this study. A simple and fast time-domain method for the FOG detection was suggested and compared with the conventional frequency-domain method. The parameters used in the FOG detection were optimized for each patient.
Results: The calculation load was 1,154 times less in the time-domain method than the conventional method, and the FOG detection performance was comparable between the two domains (P=0.79) and depended on the window length (P<0.01) and dimension of sensor information (P=0.03).
Conclusion: A minimally constraining sole-mounted sensor system was developed, and the suggested time-domain method showed comparable FOG detection performance to that of the conventional frequency-domain method. Three-dimensional sensor information and 3–4-second window length were desirable. The suggested system is expected to have more practical clinical applications.

Keywords: Parkinson’s disease, freezing of gait, acceleration, detection system, time-domain, frequency-domain

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