Back to Journals » Psoriasis: Targets and Therapy » Volume 9

A narrative review of psoriasis and multiple sclerosis: links and risks

Authors Silfvast-Kaiser AS, Homan KB, Mansouri B

Received 4 May 2019

Accepted for publication 6 August 2019

Published 22 August 2019 Volume 2019:9 Pages 81—90


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Uwe Wollina

Annika S Silfvast-Kaiser,1 Katie B Homan,2 Bobbak Mansouri3–5

1Department of Dermatology, Baylor Scott and White, Dallas, TX, USA; 2Department of Dermatology, Baylor Scott and White Medical Center, Temple, TX, USA; 3Austin Institute for Clinical Research, Pflugerville, TX, USA; 4Sanova Dermatology – Pflugerville, Pflugerville, TX, USA; 5U.S. Dermatology Partners - Tyler, TX, USA

Correspondence: Bobbak Mansouri
US Dermatology Partners - Tyler, TX 1367 Dominion Plaza, Pflugerville, TX 75703, USA
Email [email protected]

Abstract: The association of psoriasis (PsO) with other autoimmune and autoinflammatory diseases has long been a topic of interest. Although previous studies have attempted to clarify the specific relationship between PsO and multiple sclerosis (MS), it remains obscure, with limited and conflicting evidence regarding a link between the two entities. Herein, we review the etiology, pathogenesis, and treatment of each disease and present the available literature to-date regarding a possible relationship between PsO and MS. We conclude that further study is necessary to discern whether there may be a significant relationship between PsO and MS. In the meantime, clinicians may find it appropriate to screen for MS in patients with PsO, allowing for timely referral to a neurologist should it be necessary.

Keywords: psoriasis, multiple sclerosis, incidence, prevalence, links, risk factors

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]