Back to Journals » Clinical Ophthalmology » Volume 6

A comparison of the NEIVFQ25 and GQL-15 questionnaires in Nigerian glaucoma patients

Authors Mbadugha C, Onakoya A, Aribaba O, Akinsola F

Received 4 May 2012

Accepted for publication 3 July 2012

Published 3 September 2012 Volume 2012:6 Pages 1411—1419


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 5

Video abstract presented by Chigozie A Mbadugha

Views: 255

Chigozie A Mbadugha, Adeola O Onakoya, Olufisayo T Aribaba, Folashade B Akinsola

Guinness Eye Centre, Department of Ophthalmology, Lagos University Teaching Hospital, Lagos State, Nigeria

Aim: To compare two vision-specific quality of life (QOL) instruments – the disease-specific 15-item Glaucoma Quality of Life questionnaire (GQL-15) and the nonglaucoma-specific 25-item National Eye Institute Visual Function Questionnaire (NEIVFQ25).
Methods: The QOL of 132 glaucoma patients being managed in Lagos University Teaching Hospital and an equal number of controls matched for age and sex was assessed using two vision-specific instruments: GQL-15 and the NEIVFQ25. The categorization of the severity of glaucoma into mild, moderate, and severe disease was determined using the degree of visual field loss. The Statistical Package for the Social Sciences (version 15; SPSS Inc, Chicago, IL) software program was used for analyzing the data obtained. Spearman’s correlation coefficients were used to assess the correlation between the scores from the two questionnaires.
Results: Patients had the greatest difficulty with activities affected by glare and dark adaptation in the GQL-15. Driving and general vision were the factors most affected in the NEIVFQ25. The Spearman rho values showed strong correlations (rho > 0.55) between the NEIVFQ25 and GQL-15 QOL scores for the total number of participants (rho: –0.75), total number of cases (rho: –0.83), and the mild (rho: –0.76), moderate (rho: –0.75), and severe (rho: –0.84) cases. There was a moderate correlation (rho: –0.38) for QOL scores of controls. Cronbach’s alpha was 0.94 for the GQL-15 and 0.93 for the NEIVFQ25, showing high internal consistency for both questionnaires.
Conclusion: The GQL-15 and the NEIVFQ25 questionnaires showed high internal consistency, correlated strongly with each other, and were reliable in the assessment of glaucoma patients in this study.

Keywords: primary open-angle glaucoma, quality of life questionnaires, GQL-15, NEIVFQ25

Creative Commons License © 2012 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.