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A case of oculomotor nerve palsy associated with antimitotic spindle apparatus

Authors Jung, Kim U

Published 28 April 2011 Volume 2011:5 Pages 549—551

DOI https://doi.org/10.2147/OPTH.S16864

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Peer reviewer comments 2


Jong Jin Jung, Ungsoo Samuel Kim
Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea

Abstract: In this case report, we describe a case of isolated oculomotor nerve palsy associated with antibodies to mitotic spindle apparatus (anti-MSA). A 28-year-old female patient had acute, painful vertical diplopia. She had limited depression and adduction in the right eye. There was no relative afferent pupillary defect. Brain magnetic resonance imaging showed no abnormal findings. Laboratory tests were all negative, with the exception of positive anti-MSA, She had an excellent and rapid response to treatment with corticosteroids, and completely recovered after two weeks of steroid pulse therapy.

Keywords: antibodies, mitotic spindle apparatus, autoimmune disease, third nerve palsy

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