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532-nm Subthreshold Micropulse Laser for the Treatment of Chronic Central Serous Retinopathy

Authors Sousa K, Calvão-Santos G, João M, Gomes N, Falcão M

Received 23 September 2019

Accepted for publication 8 January 2020

Published 25 February 2020 Volume 2020:14 Pages 525—531

DOI https://doi.org/10.2147/OPTH.S232202

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Keissy Sousa,1 Gil Calvão-Santos,1 Marina João,2 Nuno Gomes,1 Manuel Falcão3,4

1Retina Department of Hospital de Braga, Braga, Portugal; 2Ophthalmology Department of Hospital de Braga, Braga, Portugal; 3Retina Department of Centro Hospitalar Universitário S. João, Porto, Portugal; 4Department of Surgery and Physiology of Faculty of Medicine of the University of Porto, Porto, Portugal

Correspondence: Manuel Falcão
Oftalmologia, Centro Hospitalar S. João, Alameda Prof. Hernâni Monteiro, Porto 4200-319, Portugal
Tel +351 22 551 2100
Email falcao@med.up.pt

Introduction: Subthreshold micropulse laser treatment with a 532 nm (532-SML) wavelength has been suggested as a treatment option for the treatment of chronic central serous retinopathy (cCSR). The objective is to present its effects and complications.
Methods: We present a retrospective cohort study of cCSR patients submitted to 532-SML. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) parameters – central macular thickness, subfoveal outer nuclear layer, external limiting membrane, ellipsoid band, interdigitation band, subretinal fluid and choroidal thickness – were evaluated before and 12 weeks after treatment. A power of 50%, a duty cycle of 5%, exposure time of 200 ms and a spot size of 160 μm were the applied laser parameters.
Results: We included 26 eyes. Overall there were no significant changes in visual acuity (median 0.20 (IQR 0) logMAR before and after treatment) or SD-OCT parameters. However, visual benefits occurred in 42.3% (n=11) of the patients and in half of the cases, subretinal fluid was completely reabsorbed. There were no complications.
Conclusion: In this study,  532-SML was overall ineffective on cCSR as it did not lead to significant changes in the overall median visual acuity and SD-OCT parameters. However, some patients may have benefited functionally and anatomically from the treatment; further investigation is necessary to understand the potential of 532-SML.

Keywords: central serous retinopathy, SD-OCT, subthreshold micropulse laser, 532 nm wavelength, outer retina bands

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