Back to Journals » Clinical Ophthalmology » Volume 14

532-nm Subthreshold Micropulse Laser for the Treatment of Chronic Central Serous Retinopathy

Authors Sousa K, Calvão-Santos G, João M, Gomes N, Falcão M

Received 23 September 2019

Accepted for publication 8 January 2020

Published 25 February 2020 Volume 2020:14 Pages 525—531


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Keissy Sousa,1 Gil Calvão-Santos,1 Marina João,2 Nuno Gomes,1 Manuel Falcão3,4

1Retina Department of Hospital de Braga, Braga, Portugal; 2Ophthalmology Department of Hospital de Braga, Braga, Portugal; 3Retina Department of Centro Hospitalar Universitário S. João, Porto, Portugal; 4Department of Surgery and Physiology of Faculty of Medicine of the University of Porto, Porto, Portugal

Correspondence: Manuel Falcão
Oftalmologia, Centro Hospitalar S. João, Alameda Prof. Hernâni Monteiro, Porto 4200-319, Portugal
Tel +351 22 551 2100

Introduction: Subthreshold micropulse laser treatment with a 532 nm (532-SML) wavelength has been suggested as a treatment option for the treatment of chronic central serous retinopathy (cCSR). The objective is to present its effects and complications.
Methods: We present a retrospective cohort study of cCSR patients submitted to 532-SML. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) parameters – central macular thickness, subfoveal outer nuclear layer, external limiting membrane, ellipsoid band, interdigitation band, subretinal fluid and choroidal thickness – were evaluated before and 12 weeks after treatment. A power of 50%, a duty cycle of 5%, exposure time of 200 ms and a spot size of 160 μm were the applied laser parameters.
Results: We included 26 eyes. Overall there were no significant changes in visual acuity (median 0.20 (IQR 0) logMAR before and after treatment) or SD-OCT parameters. However, visual benefits occurred in 42.3% (n=11) of the patients and in half of the cases, subretinal fluid was completely reabsorbed. There were no complications.
Conclusion: In this study,  532-SML was overall ineffective on cCSR as it did not lead to significant changes in the overall median visual acuity and SD-OCT parameters. However, some patients may have benefited functionally and anatomically from the treatment; further investigation is necessary to understand the potential of 532-SML.

Keywords: central serous retinopathy, SD-OCT, subthreshold micropulse laser, 532 nm wavelength, outer retina bands

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]