Back to Journals » Clinical Ophthalmology » Volume 13

360° ab-interno Schlemm’s canal viscodilation in primary open-angle glaucoma

Authors Ondrejka S, Körber N

Received 2 February 2019

Accepted for publication 9 May 2019

Published 15 July 2019 Volume 2019:13 Pages 1235—1246

DOI https://doi.org/10.2147/OPTH.S203917

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Simon Ondrejka,1 Norbert Körber1,2

1Augencentrum Köln, Köln, Germany; 2Eye Clinic, University Eye Hospital, Padova, Italy

Purpose: To evaluate the safety and effectiveness of ab-interno microcatheterization and 360° viscodilation of Schlemm’s canal (SC) using the VISCO360®, Viscosurgical System in treatment of primary open angle glaucoma (POAG).
Setting: Surgical center (Augencentrum Köln, Köln, Germany).
Design: Retrospective analysis of 106 eyes from 71 consecutive patients.
Methods: Ab-interno canal viscodilation (VISCO360®,) with or without cataract extraction was performed in two groups of patients with mild-moderate POAG: Group 1 had a baseline intraocular pressure (IOP) ≥18 mmHg (n=72 eyes) and Group 2 had a baseline IOP <18 mmHg (n=34 eyes). IOP without washout was measured and number of IOP-lowering medications were documented at all visits. Effectiveness was determined by reduction in IOP and reduction in the number of IOP-lowering medications at 12±3 months from baseline. Safety was determined by the rate of adverse events (AEs) and secondary surgical interventions (SSI).
Results: In Group 1, all eyes available at 12±3 months (n=72), had a 41.0% reduction in mean IOP (from 24.6±7.1 mmHg to 14.6±2.8 mmHg), 87% (n=62) of which showed an IOP reduction of ≥20% with no increase in IOP-lowering medications. In Group 2, all eyes (n=34) maintained their baseline IOP at all postoperative visits. In both groups, a significant decrease (>89%) in mean number of IOP-lowering medications was seen at 12 months with 86% of eyes completely off medication with no increase in IOP. The most common AE seen was hyphema (13%) and no eye required SSI during the study period.
Conclusion: Ab-interno SC viscodilation (VISCO360) is safe and effective in lowering IOP and reducing hypotensive medications in patients with OAG.

Keywords: 360-degree trabeculotomy, blebless, MIGS, VISCO360,® POAG, canaloplasty


Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]