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Spectral domain optical coherence tomographic findings at convalescent stage of acute zonal occult outer retinopathy

Authors Ohta K, Sato A, Fukui E

Published 20 July 2009 Volume 2009:3 Pages 423—428


Review by Single anonymous peer review

Peer reviewer comments 5

Kouichi Ohta, Atsuko Sato Emi Fukui

Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Nagano, Japan

Purpose: To describe the morphology of the retina at the convalescent stage of acute zonal occult outer retinopathy (AZOOR) from images obtained by spectral domain optical coherence tomography (SD-OCT).

Methods: The visual fields, electroretinograms (ERGs), and OCT images were reviewed in two women aged 24 and 33 years. The patients were followed for one and four years, respectively.

Results: In both cases, the anterior and posterior segments were almost normal, although both patients had a sudden unilateral vision decrease and photopsia. Goldmann perimetry revealed enlarged blind spots and scotomas. The ERGs were reduced in both cases. SD-OCT showed that the junction of the inner and outer segment, the IS/OS line, of the photoreceptors was irregular or lost in the affected retinas. The retina in these areas was thinner due to a decrease in the thickness of both the outer nuclear layer (ONL) and inner nuclear layer (INL) in Case 2.

Conclusions: The decrease in retinal thickness at the convalescent stage of AZOOR is most likely due to a shortening of not only the photoreceptors and ONL but also to a thinning of the INL in a severe case.


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