Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 6

Sleep quality predicts quality of life in chronic obstructive pulmonary disease

Authors Scharf SM, Maimon N, Simon-Tuval T, Bernhard-Scharf B, Reuveni H, Tarasiuk A

Published 22 December 2010 Volume 2011:6 Pages 1—12


Review by Single-blind

Peer reviewer comments 3

Steven M Scharf1*, Nimrod Maimon2*, Tzahit Simon-Tuval3, Barbara J Bernhard-Scharf4, Haim Reuveni2, Ariel Tarasiuk2
1Department of Pulmonary and Critical Care, University of Maryland, Baltimore, MD, USA; 2Faculty of Health Sciences, Ben-Gurion University, Beersheba, Israel; 3Guilford Glazer School of Business and Management, Ben Gurion University, Beersheba, Israel; 4Mt. Washington Pediatric Hospital, Baltimore, MD, USA; The study was performed at the Soroka University Medical Center, Beer Sheva, Israel
*Drs Scharf and Maimon contributed equally to this manuscript.

Purpose: Chronic obstructive pulmonary disease (COPD) patients may suffer from poor sleep and health-related quality of life. We hypothesized that disturbed sleep in COPD is correlated with quality of life.
Methods: In 180 patients with COPD (forced expired volume in 1 second [FEV1] 47.6 ± 15.2% predicted, 77.8% male, aged 65.9 ± 11.7 years), we administered general (Health Utilities Index 3) and disease-specific (St George’s Respiratory) questionnaires and an index of disturbed sleep (Pittsburgh Sleep Quality Index).
Results: Overall scores indicated poor general (Health Utilities Index 3: 0.52 ± 0.38), disease-specific (St George’s: 57.0 ± 21.3) quality of life and poor sleep quality (Pittsburgh 11.0 ± 5.4). Sleep time correlated with the number of respiratory and anxiety symptoms reported at night. Seventy-seven percent of the patients had Pittsburg scores >5, and the median Pittsburgh score was 12. On multivariate regression, the Pittsburgh Sleep Quality Index was an independent predictor of both the Health Utilities Index 3 and the St George’s scores, accounting for 3% and 5%, respectively, of the scores. Only approximately 25% of the patients demonstrated excessive sleepiness (Epworth Sleepiness Scale >9).
Conclusions: Most patients with COPD suffer disturbed sleep. Sleep quality was correlated with general and disease-specific quality of life. Only a minority of COPD patients complain of being sleepy.
Keywords: COPD, quality of life, Pittsburgh Sleep Quality Index, St George’s Respiratory Questionnaire, Health Utilities Index, sleep quality

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]