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Skin displacement analysis (SDA): a tool for the quantitative evaluation of skin movements elicited by underlying muscles in the face and neck area

Authors Proebstle T

Published 1 April 2011 Volume 2011:4 Pages 27—33


Review by Single anonymous peer review

Peer reviewer comments 2

Thomas M Proebstle
Department of Dermatology, University Clinic of Mainz, Mainz, Germany

Background: Quantitative numerical analysis of skin displacement triggered by muscles inserting the overlaying skin would be useful for monitoring the inhibition of mimetic muscles.
Methods: By using removable grid markings and digital photographs, skin displacement analysis (SDA) was performed on 13 patients pre-treatment and on Days 1, 2, 3, and 7 after injection of 18 units of botulinum toxin type A (BoNT/A) in the fronto-glabellar area.
Results: At baseline, amplitudes of horizontal skin displacement with fronto-glabellar contraction showed a linear increase along the eyebrow laterally from the midline; mean values (±standard deviation [SD]) 15 and 30 mm lateral to the midline were 3.2 ± 1.0 mm (range, 1.9–4.9 mm) and 6.5 ± 1.4 mm (range 4.0–8.5 mm), respectively. After injection of BoNT/A, maximum horizontal skin displacement 30 mm lateral to the midline showed a mean reduction (±SD) to 62% ± 23% at Day 2 and to 17% ± 16% at Day 7; corresponding values 15 mm lateral to the midline were 62% ± 29% and 15% ± 20%, respectively. In all cases, the reduction in horizontal skin displacement compared with pre-injection levels was statistically significant (P < 0.001).
Conclusion: SDA is a feasible method for the quantitative evaluation of skin movements elicited by muscles inserting the overlaying skin in the face and neck area.

Keywords: botulinum toxin type A, fronto-glabellar contraction, skin displacement analysis, glabellar lines

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