Randomized controlled trial about pain medication flupirtine ignores recent pharmacovigilance warnings
Authors Puljak L
Received 18 October 2017
Accepted for publication 29 November 2017
Published 12 January 2018 Volume 2018:11 Pages 177—180
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr E Alfonso Romero-Sandoval
1Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia; 2Department for Development, Research and Health Technology Assessment, Agency for Quality and Accreditation in Health Care and Social Welfare, Zagreb, Croatia
On October 16, 2017 in the Journal of Pain Research, a randomized controlled trial (RCT) comparing efficacy and safety of flupirtine versus piroxicam in postoperative pain in patients undergoing lower limb surgery was published.1 However, this paper fails to report important information.
Sowmya Chinnaiyan,1 Narayana Sarala,1 Heddur Shanthappa Arun2
1Department of Pharmacology, 2Department of Orthopedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India
We thank Livia Puljak for the valuable insights on the article titled “A comparative study of efficacy and safety of flupirtine versus piroxicam in postoperative pain in patients undergoing lower limb surgery” published in the Journal of Pain Research. The concerns highlighted in the Letter to the Editor have been answered.
View the original paper by Chinnaiyan and colleagues.
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