Professor David Dingli

Professor David Dingli

Editor-in-Chief: David Dingli

Dr Dingli is an associate professor of Medicine at Mayo Clinic where he has a joint appointment between the Division of Hematology and the Department of Molecular Medicine. He is also an adjunct professor within the Biomedical Informatics and Computational Biology (BICB) Program at the University of Minnesota, Rochester. His hematology training has taken him to the University of Glasgow Hospitals and then Mayo Clinic. For his PhD thesis, he researched the use of replication competent measles viruses for therapy of multiple myeloma. He has generated a recombinant virus that can be non-invasively tracked in vivo using molecular imaging strategies. This vector is now in clinical trials in patients with advanced myeloma. His clinical practice is devoted to patients with plasma cell disorders and chronic myeloid leukemia.

Dr Dingli’s research also includes the use of mathematical and computational models to understand tumor development and evolution, hematopoietic stem cell dynamics, and hematopoiesis as well as therapy of hematopoietic tumors with recombinant viruses and other novel agents. He trained in mathematical biology at Mayo Clinic, the University of Tennessee (Knoxville), the Santa Fe Institute, and the Program for Evolutionary Dynamics at Harvard University where he was a Mayo Clinic Scholar for two years.  He has applied mathematical and computational modeling to a variety of disorders including multiple myeloma, chronic myeloid leukemia, paroxysmal nocturnal hemoglobinuria, and cyclic hematopoiesis. 

On a national and international level, Dr Dingli is on the editorial advisory board of several journals and serves as a reviewer for many journals. He is also a reviewer for numerous funding agencies in the United States and Europe.