Prof. Dr. Subashchandrabose Chinnathambi

Department of Neurochemistry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India

Subashchandrabose Chinnathambi obtained his PhD in Biochemistry from Max Planck Institute for Structural Molecular Biology (MPASMB), Hamburg, Germany in 2011. His postdoctoral training was completed at the German Centre for Neurodegeneration Disease (DZNE) Bonn and Max Planck Institute for Neurobiological Research Cologne, Germany. After a short postdoctoral stint he joined the Biochemical Sciences Division, National Chemical Laboratory (CSIR-NCL) as a Scientist Assistant Professor. 

Prof. Dr. Chinnathambi has examined the influence of phosphorylation on the pathological conformation of human microtubule associated protein Tau in Alzheimer’s disease. His scientific interests are the physiopathology of neurodegenerative disorders, Tau Cytoskeleton, Tau-GPCR, Purinergic and Chemokine receptors, Tau stem cell, Animal models, Neuropharmacology, and Translational research. He has mainly worked with Tau protein folding and Tau oligomers internalization in microglial system. His group identified the phagocytosis of full length Tau oligomers by Actin-remodeling of activated microglia. Prof. Dr. Chinnathambi's research work has resulted in outstanding achievements with potential practical applications and publications in high-impact journals.

Prof. Dr. Chinnathambi is currently funded by various government agencies like Department of Biotechnology (DBT), Council of Scientific and Industrial Research, National Chemical Laboratory, and the Science and Education Research Board from Department of Science and Technology, Government of India. He has also worked with the National Institute of Mental Health and Neuroscience, Bangalore; Institute of National Importance (INI) funded by the Ministry of Health and Family Welfare, Government of India. Currently he is one of the Co-Principal Investigators and interested to study the blood-based biomarkers for Tauopathy in AD funded by National Institute of Aging (NIA) and National Institute of Health (NIH).

Over the years, his lab has produced a number of high quality graduate students and master interns. Prof. Dr. Chinnathambi has been awarded by CSIR-NSL research foundation the best Scientist of the year 2021, for outstanding research contribution to Tau protein in Alzheimer’s disease. He is supported by an EMBO travel grant, EuroTau 2023 travel grant and registration grant, is a DBT Neuroscience task force member, and has received many grants from Department of Biotechnology, and the Department of Science and technology from Government of India. He is part of the international grant review from Alzheimer's Society United Against Dementia, National Science Grant Belgium, National Grant France and Alzheimer’s Research UK.
Subash is part of the editorial board of various other international cell biology journals. He is also a regular invited speaker at various national and international meetings and workshops. With more than 16 years of research experience in the area of Neuroscience and Tau-related research in Alzheimer’s Disease.

Updated 28 November 2023