Dr Rongxue Wu

Department of Medicine/Cardiology, Biological Sciences Division, The University of Chicago, Chicago, IL, USA

Dr. Rongxue (Rosie) Wu is an accomplished physician-scientist and Associate Professor of Medicine (Research) at the University of Chicago. Her research focuses on vascular inflammation and endothelial barrier dysfunction, including the blood-brain barrier (BBB) and cardiac microvascular barrier dysfunction, in conditions such as sepsis, cardiac ischemia-reperfusion injury, and aging. Her work integrates genetics, signaling, and metabolism to uncover inflammation-driven mechanisms of vascular dysfunction in heart disease and aging-related disorders while exploring innovative drug development strategies using nanoparticle-based delivery and genetic approaches.

Dr. Wu earned her M.D. and Ph.D. in Molecular Biology from the University of Würzburg, Germany, and completed her postdoctoral training at Northwestern University under the mentorship of Dr. Hossein Ardehali, supported by American Heart Association (AHA) fellowships. She has received multiple research grants from the NIH and AHA. Her recent work identified an HIF-independent inflammatory pathway critical to maintaining microvascular endothelial integrity, suggesting novel therapeutic strategies for heart failure and age-related neurovascular dysfunction.

She actively contributes as a grant peer reviewer for the NIH and AHA and has reviewed manuscripts for over 50 international journals, including Nature, Circulation, ATVB, and JCI Insight. Dr. Wu is an Associate Editor for several scientific journals and has received prestigious awards, including the Rudolf Thauer Poster Prize from the German Society for Cardiology, the Young Investigator Award, and the Outstanding Junior Faculty Award at the AHA meetings.

Through her research and editorial roles, Dr. Wu continues to advance the understanding of cardiovascular and neurovascular diseases, aiming to develop innovative therapeutic strategies.

Updated 19 March 2025