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Primary Rhegmatogenous Retinal Detachment Repair by Pars Plana Vitrectomy With and Without Scleral Buckling: A Propensity Score Analysis [Response to Letter]
Authors Rajsirisongsri P, Patikulsila D 
, Phinyo P , Kunavisarut P, Chaikitmongkol V, Nanegrungsunk O, Apivatthakakul A , Seetasut S, Tantivit Y, Krisanuruks N, Sangkaew A, Watanachai N , Choovuthayakorn J
Received 8 February 2025
Accepted for publication 10 February 2025
Published 26 February 2025 Volume 2025:19 Pages 691—692
Pongthep Rajsirisongsri,1 Direk Patikulsila,1 Phichayut Phinyo,2–4 Paradee Kunavisarut,1 Voraporn Chaikitmongkol,1 Onnisa Nanegrungsunk,1 Atitaya Apivatthakakul,1 Sutheerada Seetasut,1 Yaowaret Tantivit,1 Napatsorn Krisanuruks,1 Apisara Sangkaew,1 Nawat Watanachai,5 Janejit Choovuthayakorn1
1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2Clinical Epidemiology and Clinical Statistics Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 3Department of Biomedical Informatics and Clinical Epidemiology (Bioce), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 4Musculoskeletal Science and Translational Research (MSTR), Chiang Mai University, Chiang Mai, Thailand; 5Department of Ophthalmology, Faculty of Medicine, Mahidol University, Bangkok, Thailand
Correspondence: Janejit Choovuthayakorn, Email [email protected]
View the original paper by Dr Rajsirisongsri and colleagues
This is in response to the Letter to the Editor
Dear editor
We thank Visioli et al for their interest in our research and their insightful comments regarding propensity score (PS) methodology. As noted, PS analysis serves as a strategy to reduce surgical selection bias that might be introduced by surgeons in observational studies. However, only a small number of authors have applied this method to examine outcomes and complications associated with retinal detachment repair.1–3
Concerning the questions regarding our PS approaches and variable selection in this research, we provide responses here. Both PS matching and Inverse Probability of Treatment Weighting (IPTW) yield effective case analyses, yet they differ in their strategies for balancing treatment groups. PS matching necessitates excluding unmatched data, which consequently decreases the sample size. IPTW, conversely, retains the entire dataset, thus preserving statistical power while achieving balance through weighting. Additionally, IPTW generates population-level treatment effects directly, eliminating the additional marginalization steps necessary in PS matching.4 These advantages led us to utilize IPTW for analyzing treatment effects while retaining our full dataset. In selecting covariates, discussions were held with co-authors, and the parameters were incorporated following a review of previous studies.1,2
We agree that the lack of consistency in adjusting preoperative factors of PS for retinal detachment repair found in literature may hinder methodological clarity. In further studies, generating standardized preoperative PS parameters based on expert consensus in this area may greatly improve PS methodology in surgical decision-making for retinal detachment repair.
By acknowledging the fundamental importance of surgeon expertise and preferences in retinal detachment surgical decisions, we view PS analysis as a valuable complementary tool for evaluating outcomes in these cases.
Disclosure
Dr Onnisa Nanegrungsunk reports grants, personal fees from Bayer, personal fees from Roche, personal fees from AbbVie, outside the submitted work. The author(s) report no conflicts of interest in this communication.
References
1. Kawano S, Imai T, Sakamoto T; Group J-RDR. Scleral buckling versus pars plana vitrectomy in simple phakic macula-on retinal detachment: a propensity score-matched, registry-based study. Br J Ophthalmol. 2022;106:857–862. doi:10.1136/bjophthalmol-2020-318451
2. Sanabria MR, Fernández I, Sala-Puigdollers A, et al. A propensity score matching application: indications and results of adding scleral buckle to vitrectomy: the Retina 1 Project: report 3. Eur J Ophthalmol. 2012;22:244–253. doi:10.5301/EJO.2011.6528
3. Gharbiya M, Visioli G, Iannetti L, et al. Comparison between scleral buckling and vitrectomy in the onset of cystoid macular edema and epiretinal membrane after rhegmatogenous retinal detachment repair. Retina. 2022;42:1268–1276. doi:10.1097/IAE.0000000000003475
4. Chesnaye NC, Stel VS, Tripepi G, et al. An introduction to inverse probability of treatment weighting in observational research. Clin Kidney J. 2022;15:14–20. doi:10.1093/ckj/sfab158
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