Back to Journals » Neuropsychiatric Disease and Treatment » Volume 8

Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria

Authors Mura M, Castagna A, Fontani V, Rinaldi S

Received 16 January 2012

Accepted for publication 2 March 2012

Published 4 April 2012 Volume 2012:8 Pages 149—154

DOI https://doi.org/10.2147/NDT.S29971

Review by Single-blind

Peer reviewer comments 3

Marco Mura1, Alessandro Castagna2, Vania Fontani2, Salvatore Rinaldi2

1Institute of Radiology, University of Cagliari, 2Rinaldi Fontani Institute – Department of Neuro Psycho Physical Optimization, Florence, Italy

Purpose: This study assessed changes in functional dysmetria (FD) and in brain activation observable by functional magnetic resonance imaging (fMRI) during a leg flexion-extension motor task following brain stimulation with a single radioelectric asymmetric conveyer (REAC) pulse, according to the precisely defined neuropostural optimization (NPO) protocol.
Population and methods: Ten healthy volunteers were assessed using fMRI conducted during a simple motor task before and immediately after delivery of a single REAC-NPO pulse. The motor task consisted of a flexion-extension movement of the legs with the knees bent. FD signs and brain activation patterns were compared before and after REAC-NPO.
Results: A single 250-millisecond REAC-NPO treatment alleviated FD, as evidenced by patellar asymmetry during a sit-up motion, and modulated activity patterns in the brain, particularly in the cerebellum, during the performance of the motor task.
Conclusion: Activity in brain areas involved in motor control and coordination, including the cerebellum, is altered by administration of a REAC-NPO treatment and this effect is accompanied by an alleviation of FD.

Keywords: motor behavior, motor control, cerebellum, dysmetria, functional dysmetria, fluctuating asymmetry

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment

Maioli M, Contini G, Santaniello S, Bandiera P, Pigliaru G, Sanna R, Rinaldi S, Delitala AP, Montella A, Bagella L, Ventura C

Drug Design, Development and Therapy 2013, 7:1063-1073

Published Date: 27 September 2013

Effects of regenerative radioelectric asymmetric conveyer treatment on human normal and osteoarthritic chondrocytes exposed to IL-1β. A biochemical and morphological study

Collodel G, Fioravanti A, Pascarelli NA, Lamboglia A, Fontani V, Maioli M, Santaniello S, Pigliaru G, Castagna A, Moretti E, Iacoponi F, Rinaldi S, Ventura C

Clinical Interventions in Aging 2013, 8:309-316

Published Date: 19 March 2013

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study

Rinaldi S, Maioli M, Santaniello S, Castagna A, Pigliaru GF, Gualini S, Margotti ML, Carta A, Fontani V, Ventura C

Clinical Interventions in Aging 2012, 7:191-194

Published Date: 29 June 2012

Social anxiety disorder: radio electric asymmetric conveyor brain stimulation versus sertraline

Fontani V, Mannu P, Castagna A, Rinaldi S

Patient Preference and Adherence 2011, 5:581-586

Published Date: 22 November 2011

Noninvasive brain stimulation by radioelectric asymmetric conveyor in the treatment of agoraphobia: open-label, naturalistic study

Mannu P, Rinaldi S, Fontani V, Castagna A, Lotti Margotti M

Patient Preference and Adherence 2011, 5:575-580

Published Date: 18 November 2011

Radioelectric asymmetric stimulation of tissues as treatment for post-traumatic injury symptoms

Fontani V, Castagna A, Mannu P, Rinaldi S

International Journal of General Medicine 2011, 4:627-634

Published Date: 26 August 2011

Radio electric tissue optimization in the treatment of surgical wounds

Castagna A, Fontani V, Rinaldi S, Mannu P

Clinical, Cosmetic and Investigational Dermatology 2011, 4:133-137

Published Date: 25 August 2011

Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study

Olivieri E, Vecchiato C, Ignaccolo N, Mannu P, Castagna A, Aravagli L, Fontani V, Rinaldi S.

Neuropsychiatric Disease and Treatment 2011, 7:449-455

Published Date: 4 August 2011

Comparison of two treatments for coxarthrosis: local hyperthermia versus radio electric asymmetrical brain stimulation

Castagna A, Rinaldi S, Fontani V, Mannu P, Lotti Margotti M

Clinical Interventions in Aging 2011, 6:201-206

Published Date: 25 July 2011

Radioelectric asymmetric brain stimulation and lingual apex repositioning in patients with atypical deglutition

Castagna A, Rinaldi S, Fontani V, Mannu P

Journal of Multidisciplinary Healthcare 2011, 4:209-213

Published Date: 21 June 2011

Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor

Mannu P, Rinaldi S, Fontani V, Castagna A

Neuropsychiatric Disease and Treatment 2011, 7:373-379

Published Date: 15 June 2011

Readers of this article also read:

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010