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Preference for Easyhaler® Over Previous Dry Powder Inhalers in Asthma Patients: Results of the DPI PREFER Observational Study

Authors Alvarez-Gutiérrez FJ, Gómez-Bastero Fernández A, Medina Gallardo JF, Campo Sien C, Rytilä P, Delgado Romero J

Received 23 December 2020

Accepted for publication 30 January 2021

Published 16 February 2021 Volume 2021:15 Pages 349—358

DOI https://doi.org/10.2147/PPA.S295710

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen


Francisco Javier Alvarez-Gutiérrez,1 Ana Gómez-Bastero Fernández,2 Juan Francisco Medina Gallardo,1 Carlos Campo Sien,3 Paula Rytilä,4 Julio Delgado Romero5

1Unidad de Asma, Hospital Universitario Virgen del Rocio, Sevilla, Spain; 2Unidad de Asma, Hospital Universitario Virgen Macarena, Sevilla, Spain; 3Orion Pharma Iberia, Madrid, Spain; 4Orion Pharma Corporate, Espoo, Finlandia; 5Unidad de Gestión Clinica Alergología, Hospital Virgen Macarena, Sevilla, Spain

Correspondence: Francisco Javier Alvarez-Gutiérrez
Unidad de Asma, Hospital Universitario Virgen del Rocio, Av. Manuel Siurot, S/n, Sevilla, 41013, Spain
Email fjavieralvarez2008@gmail.com

Objective: To study patient preference for and satisfaction with the Easyhaler® device and to assess ease of training and use of the inhaler in patients previously treated with a variety of dry powder inhalers (DPIs).
Methods: We designed a non-interventional, cross-sectional, single-visit observational study of adult patients with persistent asthma referred to specialized care who had previously been treated with DPI inhalers for at least 3 months. Once clinical baseline data had been checked, patients filled in questionnaires on asthma control (GINA 2019), Feeling of Satisfaction with the Inhaler (FSI-10), and adherence (TAI and Morisky-Green questionnaires). Thereafter, all patients were trained in the use of Easyhaler. We assessed ease of use and satisfaction (FSI-10) with Easyhaler, as well as inhaler device preferences.
Results: We recruited 502 patients (mean age, 50.2 ± 16.2 y; 63.1% female), of whom 485 were evaluable. In response to the main objective of the study, we compared the values of the self-completed adapted FSI-10, to measure satisfaction with the inhaler. A significantly higher score in each item of the questionnaire was recorded for Easyhaler. Overall, 38% of patients showed exclusive preference for Easyhaler (compared with 15% for the previous device) or were evenly matched in 46% of cases.
Conclusion: In the present study, Easyhaler achieved better patient ratings in terms of preference and satisfaction than previously used DPI devices. In order to improve asthma adherence strategies, patient preferences and device choice should be taken into account.

Keywords: patient satisfaction, adherence, inhaler devices, dry powder inhalers, asthma control, clinical outcomes

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