Back to Journals » Vascular Health and Risk Management » Volume 14

Postural tachycardia syndrome: current perspectives

Authors Wells R, Spurrier AJ, Linz D, Gallagher C, Mahajan R, Sanders P, Page A, Lau DH

Received 6 September 2017

Accepted for publication 20 October 2017

Published 29 December 2017 Volume 2018:14 Pages 1—11

DOI https://doi.org/10.2147/VHRM.S127393

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Amudha Kadirvelu


Rachel Wells,1,2 Andrew J Spurrier,3 Dominik Linz,1 Celine Gallagher,1 Rajiv Mahajan,1 Prashanthan Sanders,1 Amanda Page,4 Dennis H Lau1

1Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Departments of Cardiology and Medicine, Royal Adelaide Hospital, 2Department of Medicine, Royal Adelaide Hospital, 3Sound Radiology, 4Centre for Nutrition and Gastrointestinal Diseases, University of Adelaide, Adelaide, SA, Australia

Abstract: Postural tachycardia syndrome (POTS) is the combination of an exaggerated heart rate response to standing, in association with symptoms of lightheadedness or pre-syncope that improve when recumbent. The condition is often associated with fatigue and brain fog, resulting in significant disruptions at a critical time of diagnosis in adolescence and young adulthood. The heterogeneity of the underlying pathophysiology and the variable response to therapeutic interventions make management of this condition challenging for both patients and physicians alike. Here, we aim to review the factors and mechanisms that may contribute to the symptoms and signs of POTS and to present our perspectives on the clinical approach toward the diagnosis and management of this complex syndrome.

Keywords: orthostatic, autonomic, hypermobility, baroreflex, doppler

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]