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Possible Prosthetic Valve Endocarditis by Pandoraea pnomenusa and Specific Virulence Mechanisms

Authors Bodendoerfer E, Personnic N, Mestres CA, Wilhelm MJ, Meyer L, Hasse B

Received 8 January 2021

Accepted for publication 24 February 2021

Published 6 April 2021 Volume 2021:14 Pages 1319—1324


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony

Elias Bodendoerfer, 1 Nicolas Personnic, 1 Carlos A Mestres, 2 Markus J Wilhelm, 2 Lilly Meyer, 3 Barbara Hasse 3

1University of Zurich, Institute of Medical Microbiology, Zurich, Switzerland; 2University Hospital Zurich, Clinic for Cardiac Surgery, Zurich, Switzerland; 3University Hospital Zurich, Department of Infectious Diseases and Hospital Epidemiology, Zurich, Switzerland

Correspondence: Elias Bodendoerfer
Institute of Medical Microbiology, University of Zurich, Gloriastrasse 28/30, Zürich, CH-8006, Switzerland
Tel +41 44 634 26 18
Email [email protected]

Abstract: Bacteremia by Pandoraea spp. has rarely been described before. We report the first case of a P. pnomenusa possible prosthetic valve endocarditis, according to the modified Duke criteria, in a 37-year old male injecting drug user suffering from recurrent endocarditis. Furthermore, we demonstrate biofilm formation by the P. pnomenusa isolates of this patient and investigate antibiotic resistance.

Keywords: prosthetic valve endocarditis, central venous catheter, bacteremia, Pandoraea pnomenusa, biofilm formation, antibiotic resistance

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