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Pediatric neurocysticercosis: current challenges and future prospects

Authors Singhi P, GAHLOT A

Received 18 August 2015

Accepted for publication 13 November 2015

Published 8 March 2016 Volume 2016:7 Pages 5—16

DOI https://doi.org/10.2147/PHMT.S79058

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Francesco Morini

Peer reviewer comments 2

Editor who approved publication: Professor Laurens Holmes, Jr


Pratibha Singhi, Arushi Gahlot Saini

Department of Pediatrics, Pediatric Neurology and Neurodevelopment Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Abstract: Neurocysticercosis (NCC) is an acquired infection of the nervous system caused by encysted larvae of Taenia solium. It is a major cause of epilepsy in the tropics and the commonest cause of focal seizures in North Indian children. T. solium teniasis-cysticercosis is considered a parasitic “Neglected Tropical Diseases” endemic throughout Southeast Asia. NCC in children has pleomorphic manifestations depending on the location, number and viability of the cysts, and host response. Even with advancing knowledge of the disease manifestations, many aspects related to diagnosis and treatment, particularly in children, still remain controversial and pose challenges to clinical practice. There is no gold standard test to diagnose NCC and the management recommendations are still emerging. This review provides an overview of diagnosis of NCC in children and its management with special focus on current challenges and future prospects.

Keywords: neurocysticercosis, children, epilepsy, ring enhancing lesions, pigs

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