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Orbital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature

Authors Mulay K, Ali MJ , Reddy VA, Honavar SG

Received 18 September 2012

Accepted for publication 23 October 2012

Published 11 December 2012 Volume 2012:6 Pages 2049—2057


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Kaustubh Mulay,1 Mohammad Javed Ali,2 Vijay Anand Reddy,2 Santosh G Honavar2

1Ocular Pathology Service, LV Prasad Eye Institute, Hyderabad, Andhra Pradesh, India; 2Oncology Service, LV Prasad Eye Institute, Hyderabad, Andhra Padresh, India

Abstract: Ocular involvement by plasmablastic lymphoma is extremely rare with very few reports in the literature. Its morphological and immunological resemblance to plasma cell myeloma makes it a diagnostic challenge, while its clinical course, which is characterized by recurrence and death, makes therapy a challenge for clinicians. We present three cases of plasmablastic lymphoma, each of which has distinct clinicoradiological features, and we also review the literature on orbital plasmablastic lymphomas.

Keywords: plasmablastic lymphoma, ocular, myeloma, orbit

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