Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
Received 6 February 2019
Accepted for publication 8 May 2019
Published 18 June 2019 Volume 2019:13 Pages 1027—1031
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Suthasinee Sinawat,1 Thawinee Trisakul,1 Stephanie Choi,2 Michael Morley,2 Supat Sinawat,3 Yosanan Yospaiboon1
1KKU Eye Center, Department of Ophthalmology, Khon Kaen University, Khon Kaen, Thailand; 2Harvard Medical School, Boston, MA, USA; 3Department of Physiology, Khon Kaen University, Khon Kaen, Thailand
Purpose: To elucidate the clinical manifestations, management, and visual outcomes of patients with ocular angiostrongyliasis.
Methods: This was a single-center retrospective study of patients with ocular angiostrongyliasis presenting between 1995 and 2017 at Srinagarind Hospital, Khon Kaen, Thailand. Cases were found based on a search of diagnostic codes. A total of 18 patients were diagnosed through identification of the Angiostrongylus cantonensis parasite within the eye. Medical records and ocular photography were reviewed.
Results: There were 18 cases, with a mean age of 40.7±14.2 years. All patients had a history of raw food ingestion, such as snails. Most of the patients presented with blurred vision: 13 cases (72.22%) had best-corrected visual acuity of 2/60 or worse. Only one living larva was detected in each case. The size of larvae varied widely from 2.6–12.6 mm in length. Larvae were commonly detected in the vitreous cavity. Although multiple treatment modalities were used, including focal laser, surgery, antihelminthic drugs, and steroid treatment, the majority of cases (70.6%) did not have visual improvement.
Conclusion: Focal laser is recommended to eradicate subretinal angiostrongyliasis, while laser treatment prior to surgical removal is recommended to eliminate intracameral and intravitreal angiostrongyliasis. Pulse methylprednisolone therapy may be beneficial in cases of acute optic neuritis. The visual prognosis mainly depends on ocular pathology and parasitic migration pathway.
Keywords: Angiostrongylus canthnensis, intraocular parasite, raw food, ocular angiostrongyliasis
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]