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Nephrotic presentation in hydatid cyst disease with predominant tubulointerstital disease

Authors Aziz F, Pandya T, Patel HV, Ramakrishna P, Goplani KR, Gumber M, Vanikar AV, Kanodia K, Shah PR, Trivedi HL

Published 25 June 2009 Volume 2009:2 Pages 23—26


Review by Single anonymous peer review

Peer reviewer comments 2

Feroz Aziz1, Tanmay Pandya1, Himanshu V Patel1, Paladugu Ramakrishna1, Kamal R Goplani1, Manoj Gumber1, Aruna V Vanikar2,  Kamal Kanodia2, Pankaj R Shah1, Hargovind L Trivedi1

1Department of Nephrology and Transplantation Medicine; 2Department of Pathology, Lab Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC), Ahmedabad, Gujarat, India

Abstract: Renal involvement, which can rarely occur in echinococcosis, more commonly manifests as hydatid cyst of the kidney. Scattered case reports of nephrotic syndrome secondary to hydatid cyst in the liver or lung have been reported for over two decades. The glomerular picture varied from minimal change lesion to mesangiocapillary glomerulonephritis. We report a case of predominantly tubulointerstitial nephritis with mesangioproliferative glomerulonephritis in a patient with hepatic hydatid cyst which responded to cyst resection alone.

Keywords: echinococcosis, hydatid cyst, kidney, nephrotic syndrome, tubulointerstitial nephritis

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