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Journal of Asthma and Allergy

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ISSN: 1178-6965

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Treatable Traits in Asthma and Upper Airway Disease

The treatable traits approach offers a pragmatic framework to identify measurable and modifiable factors that contribute to exacerbations, corticosteroid burden, impaired quality of life, and variable treatment response in asthma. These traits may include airway inflammatory patterns, allergic sensitization, mucus hypersecretion, airflow limitation, and extra-bronchial comorbidities. Among these, upper airway diseases such as allergic rhinitis, chronic rhinosinusitis, and nasal polyposis are particularly relevant, reflecting the close anatomical, immunological, and clinical links between the upper and lower airways.