Back to Journals » Clinical Ophthalmology » Volume 4

Hyperbaric oxygen therapy for the treatment of radiation-induced macular ischemia

Authors Haji S, Frenkel MP

Published 10 May 2010 Volume 2010:4 Pages 433—436


Review by Single anonymous peer review

Peer reviewer comments 3

Shamim A Haji1,2, Ronald EP Frenkel1,2,3

1Eye Research Foundation, Stuart, FL, USA; 2East Florida Eye Institute, Stuart, FL, USA; 3Bascom Palmer Eye Institute, Miami, FL, USA

Purpose: To report a case of radiation-induced macular ischemia where vision and macular perfusion improved after hyperbaric oxygen (HBO) therapy.

Methods: A 62-year-old male patient developed radiation-induced macular ischemia after he was treated with radiation for brain glioma. The patient presented with best spectacle-corrected visual acuity (BSCVA) acuity of 20/400 in his right eye. Optical coherence tomography (OCT) showed central macular thickness of 468 μm. The patient received focal laser, intravitreal triamcinolone, and HBO therapy.

Results: The patient’s vision improved from 20/400 to 20/100 after focal laser and intravitreal triamcinolone. His central macular thickness improved from 468 μm to 132 μm. After receiving HBO therapy, his VA improved to 20/50 and fluorescein angiography showed improvement in macular perfusion.

Conclusion: HBO therapy improves macular perfusion in patients with radiation-induced macular ischemia.

Keywords: macular ischemia, visual acuity, hyperbaric oxygen therapy, macular perfusion

Creative Commons License © 2010 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.