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Heart rate variability and incidence of depression during the first six months following first myocardial infarction

Authors Wilkowska A, Rynkiewicz A, Wdowczyk J, Landowski J, Cubała WJ

Received 16 April 2019

Accepted for publication 22 May 2019

Published 10 July 2019 Volume 2019:15 Pages 1951—1956

DOI https://doi.org/10.2147/NDT.S212528

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Prof. Dr. Roumen Kirov

Peer reviewer comments 2

Editor who approved publication: Dr Roger Pinder


Alina Wilkowska,1 Andrzej Rynkiewicz,2 Joanna Wdowczyk,3 Jerzy Landowski,1 Wiesław Jerzy Cubała1

1Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdańsk, Poland; 2Department of Cardiology and Cardiosurgery, Faculty of Medicine, University of Warmia and Mazury, Olsztyn, Poland; 3First Department of Cardiology, Faculty of Medicine, Medical University of Gdansk, Gdańsk, Poland

Background: Post-myocardial depression is a highly prevalent condition worsening the course and prognosis of coronary artery disease. One of the possible pathogenetic factors is dysregulation of the autonomous nervous system, resulting in heart rate variability reduction.
Methods: Twenty two patients hospitalised due to a first myocardial infarction were included. The Beck Depression Inventory (BDI) was used to rate the severity of their depressive symptoms.
Results: Depressive symptomatology, defined as BDI ≥10, was present in 36.3% of the patients. Increase in heart rate variability (HRV) was observed in both groups during the first 6 months after the myocardial infarction. The HRV was significantly lower in the depressed group compared to patients without depression.
Conclusion: Presence of depression after the myocardial infarction (MI) is associated with a significant decrease of the time domain HRV measure SDNN (standard deviation of all normal RR intervals) and with its slower increase during at least a three months period.

Keywords: depression, myocardial infarction, autonomic nervous system, heart rate variability


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