Back to Journals » Clinical Ophthalmology » Volume 4

Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

Authors Theocharis I

Published 16 February 2010 Volume 2010:4 Pages 73—76


Review by Single anonymous peer review

Peer reviewer comments 2

IP Theocharis

Ophthalmology Department, Iaso General Hospital, Athens, Greece

Purpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).
Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;
Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.
Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.
Keywords: fibrinogen, retinal detachment, pathogenesis

Creative Commons License © 2010 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.