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Evaluation of external pressure to the sacral region in the lithotomy position using the noninvasive pressure distribution measurement system

Authors Mizuno J , Takahashi T

Received 16 September 2016

Accepted for publication 26 January 2017

Published 17 February 2017 Volume 2017:13 Pages 207—213

DOI https://doi.org/10.2147/TCRM.S122489

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Garry Walsh

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Ju Mizuno,1 Toru Takahashi2

1Department of Anesthesiology and Pain Medicine, Juntendo University, Faculty of Medicine, Bunkyo-ku, Tokyo, 2Faculty of Health and Welfare Science, Okayama Prefectural University, Soja-shi, Okayama, Japan

Background: Pressure ulcers (PUs) in the sacral region can be a complication of surgical procedures performed in the lithotomy position. Previous reports have noted a difference between men and women in PU development related to the supine position, and body weight and body mass index (BMI) have been also described as known risk factors in supine position-related PU development. The BIG-MAT® system is a noninvasive pressure distribution measurement device used to measure external pressure (EP). We used this system to investigate the relationship between EP to the sacral region in the lithotomy position and selected physical characteristics.
Methods: We recruited 21 young, healthy volunteers (11 men and 10 women, aged 21.4±0.5 years). Using the BIG-MAT system, we measured four types of EP to the sacral region: box pressure, peak box pressure, contact pressure, and peak contact pressure. We analyzed the relationships between these dynamic parameters and physical characteristics of the participants.
Results: There were no differences between men and women in the four types of EP, and no significant differences related to the participants’ height, weight, or BMI.
Conclusion: An individual’s height, weight, and BMI may not contribute to the risk of inducing lithotomy position-related PUs in the sacral region. The noninvasive pressure distribution measurement system BIG-MAT for patients in the lithotomy position during surgery could become a significant device when estimating EP at the sacral region.

Keywords: lithotomy position-related pressure ulcer, noninvasive pressure distribution measurement device, peak contact pressure, physical characteristics

 

Introduction

Pressure ulcers (PUs) are localized injuries to the skin and underlying tissue that generally occur over a bony prominence as a result of external pressure (EP) either alone or in combination with shear forces and friction. PUs are also known as pressure sores, bedsores, and decubitus ulcers. PUs develop when a persisting EP on bony prominences obstructs healthy capillary flow, leading to tissue necrosis.1 Mild EP sores may be experienced by healthy individuals who are restrained over time in a single position. Supine position-related PUs most commonly develop in individuals who are unable to move about, such as those who are bedridden. The most common location for PUs is the sacral region,2 reported to be the site of 22%3 or 38%4 of all PUs.

Patients who undergo prolonged surgical procedures are immobilized for long periods and are therefore at risk of developing PUs. The development of PUs has been explored in only a small proportion of surgical patients.5 The lithotomy position is often used to operate on pelvic viscera and the perineum in urologic, colorectal, and gynecologic surgeries. PUs in the sacral region occasionally occur after prolonged surgical procedures performed in this position.6

It is widely believed that a number of factors can influence the tolerance of skin to EP, thereby increasing the risk of supine position-related PU development, and so, knowing a patient’s physical characteristics is important. A study has reported that a difference exists between men and women in PU development, and low weight is considered to be a significant and distinct risk factor.7 Indeed, there is a higher prevalence of PUs not only in patients with low weight and low body mass index (BMI), but also in overweight patients.8 It has been reported that obese patients are at a higher risk of developing serious PUs than nonobese patients.9 However, it remains unclear why only certain patients develop PUs. Unfortunately, no published studies are available on the impact of sex and physical characteristics on PUs in patients in the lithotomy position. Therefore, further studies in this field are needed to expand the current knowledge base. We hypothesized that lithotomy position-related PUs are induced by patients’ physical characteristics.

Major preventive interventions consist of removing or redistributing the pressure-sensitive areas of the body. Pressure relief is known to be the single most important factor in the prevention of PUs.5 The pressure distribution measurement system BIG-MAT® (Nitta Corp., Osaka, Japan) is a noninvasive method for measuring EP that was designed for industrial applications.10 In our previous studies, we have used the BIG-MAT system to measure the EP in fibular regions to investigate the cause of peroneal nerve paralysis11,12 and in the calf region to investigate the cause of well leg compartment syndrome13 associated with the lithotomy position.

In this study, we used the BIG-MAT system to investigate relationship between the EP applied to the sacral region with participants in the lithotomy position and a series of physical characteristics. The aim of this study was to identify potential risk factors for lithotomy position-related PUs in the sacral region in order to suggest prevention strategies.

Methods

This study was approved by the Ethics Committee of Okayama Prefectural University (approval No 307). We recruited 21 young, healthy university students (11 men and 10 women, aged 21–22 years) as volunteers, and written informed consent was obtained from the participants before starting the study including publication of images and data. We measured the height, weight, and BMI of each participant.

The BIG-MAT system comprises a pressure distribution measurement sheet with 2,112 (44×48) sensors (BIG-MAT2000P3BS®; dimensions L 440, W 480, D 0.4 mm), a sensor connector, and a personal computer (PC) with built-in BIG-MAT software (Figure 1). The system was calibrated by careful placement of a 25 kg concrete block.

Figure 1 BIG-MAT® pressure distribution measurement system.
Note: The system comprises the BIG-MAT2000P3BS® sheet, a sensor connector, and a PC with built-in BIG-MAT software.
Abbreviation: PC, personal computer.

The BIG-MAT2000P3BS sheet was placed on the mattress of an electric operating table class IB® (Takara Belmont Corp., Osaka, Japan). The 3 cm thick mattress was made from flexible polyurethane foam in a single-layer structure. During measurements, the participant was asked to lie on the table in the lithotomy position (Figure 2). Both knees and lower legs were placed on a knee-crutch-type leg holder (KCLH) system Knee Crutch® (Takara Belmont Corp.). By using the angle gauge, both hip joints were flexed at 90° from the trunk, externally rotated at 40° from the midline, and abducted at 20°; both knee joints were flexed at 90° until both lower legs were parallel to the table surface.14 After having been in the lithotomy position for 5 minutes, the participants remained in the same position for an additional minute while the measurements were being performed. The participants were kept awake throughout.

Figure 2 Lithotomy position.
Notes: The participant’s pelvis was positioned on a BIG-MAT2000P3BS® sheet placed on the operating table mattress. The 3 cm mattress was made from flexible polyurethane foam in a single-layer structure; the table was an electric operating table class IB®.

We measured and recorded the EP distribution at the sacral region using the BIG-MAT system in the neutral state. Digital measurement values were converted to pressure information by the software, which displayed two-dimensional, visually understandable squares for each of the 2,112 sensor cells. Outputs from all sensor cells were also displayed as a number in the range 0–255. Changes in pressure values were consecutively recorded, and chronological changes were saved as movie files on the PC. We recorded 100 pressure distribution views for each participant, followed by measurement of the pressure distribution for the BIG-MAT2000P3BS sheet.

Figure 3 shows a representative view of the pressure distribution. We selected a square area of the display (the box) corresponding to the sacral region for analysis, and evaluated the total force on the sensor cells within the box, and four measures of EP: the box pressure (BP), peak box pressure (PBP), contact pressure (CP), and peak contact pressure (PCP). BP represented the mean pressure on the sensor cells inside the box, which was equal to the total force applied in the box divided by the total area of the box. PBP represented the mean pressure on 2×2 loaded sensor cells that corresponded with the highest pressure within the box (peak area), which was equal to the total force in these four squares divided by the peak area. CP represented the mean pressure on the loaded sensor cells inside the box, which was equal to the total force divided by the area covered by the loaded sensor cell. PCP represented the mean pressure on the loaded sensor cells within the peak area, which was equal to the total force in the four squares divided by the loaded sensor cell area within the peak area.

Figure 3 Representative view of the pressure distribution at the surface of the sacral region with the participant in the lithotomy position.
Notes: The pressure was measured and recorded using the BIG-MAT® system. High-pressure areas are shown with red squares and low-pressure areas with blue squares. The black square box indicates the sacral region used in the analysis.

Analyses were performed using Excel 2013® (Microsoft Corp., Redmond, WA, USA) and Deltagraph 5.4.5v J® (Deltapoint Inc., Monterey, CA, USA). BMI was calculated as the participant’s weight (kg) divided by the square of their height (m). Values were expressed as mean ± standard deviation. Unpaired Student’s t-tests were used for statistical comparisons between the men and women. Simple linear regression analyses were performed to determine correlations between the total force, BP, PBP, CP, and PCP, and participant-specific physical characteristics, such as sex, height, weight, and BMI. A P-value of <0.05 was considered to be significant.

Results

The age, sex, height, weight, and BMI of the 21 volunteers are shown in Table 1. There were no sex differences in the total force, BP, PBP, CP, and PCP on the sacral region (Table 2). No significant linear correlations were observed between the total force, BP, PBP, CP, or PCP and the participants’ height (P=0.76, 0.47, 0.67, 0.28, and 0.67, respectively), weight (P=0.58, 0.39, 0.93, 0.23, and 0.93, respectively), or BMI (P=0.21, 0.51, 0.63, 0.40, and 0.63, respectively).

Table 1 Participant characteristics
Notes: *P<0.05, **P<0.001 compared with women. Data are expressed as mean ± standard deviation, with the minimum and maximum values shown in parentheses.
Abbreviation: BMI, body mass index.

Table 2 Total force and the four types of external pressure on the sacral region with participants lying in the lithotomy position
Note: Data are expressed as mean ± standard deviation, with the minimum and maximum values shown in parentheses.
Abbreviations: BP, box pressure; CP, contact pressure; PBP, peak box pressure; PCP, peak contact pressure.

Discussion

The primary novel finding of this study was that there were no sex differences in the four types of EP measured using the BIG-MAT system in the lithotomy position. Furthermore, there were no significant correlations between the measured EPs and the participants’ height, weight, or BMI.

Capillary blood pressure

EP applied over an area of the body, especially over bony prominences, can lead to obstruction of the capillary vessels. This deprives tissues of oxygen and nutrients, causing ischemia (deficiency of blood in a particular area), hypoxia (inadequate amount of oxygen available to the cells), edema, inflammation, and, ultimately, necrosis and ulcer formation. Thus, PUs are caused by EP applied to soft tissue that results in completely or partially obstructed blood flow to the tissue.

Excessive pressure for a period of time may result in the development of PUs. Previous studies have reported that capillary blood pressure was 32 mmHg with microinjection in human skin15 and 25 mmHg in canine muscle.16 Therefore, it is generally accepted that healthy capillary pressure ranges from 20 to 40 mmHg, with 32 mmHg being considered the average.1 If the EP exceeds 32 mmHg, it will induce occlusion of the capillary vessel, resulting in ischemic injury. It has been recommended that EP loading to the skin surface be kept below 32 mmHg and as low as possible.17 In addition, when a person is lying down, EPs may approach the diastolic blood pressure under bony prominences.18 Tissue interface pressure, that is, the force per unit area that acts perpendicularly between the body and the patient’s support surface at bony prominences, is extremely high near the sacral area in patients who undergo prolonged surgical procedures. In our present results, the mean value of PCP on the sacral region with the participants in the lithotomy position was 93.3 mmHg. This value was significantly >32 mmHg (P<0.001) and probably the diastolic blood pressure and was similar to the value of EP measured physiologically in our previous studies.1113 From this result, it would be expected that operation in the lithotomy position can cause position-related PUs.

Sex

We found no sex difference in the total force and the four types of EP. In a previous study, logistic regression analysis demonstrated that sex did not predict PUs on admission to university-operated tertiary care hospitals, medical centers, and skilled nursing homes.19 Studies reported that sex was not significantly associated with the presence of PUs in university teaching hospitals20 and intensive care unit (ICU).21 According to logistic regression analysis, sex was not a significant predictor of PUs in hospital settings.22 Thus, sex difference may not affect EP on the sacral region in the lithotomy position.

However, it has been reported that people older than 65 years have the risk for PUs, with a prevalence of 37 and 52 per 100,000 population for men and women, respectively.2 Unadjusted analyses from a population-based retrospective cohort study revealed statistically significant associations with sex of the incidence of hospital-acquired PUs.23 In univariate and multivariate analyses, the female sex was associated with hospital-acquired PUs.24 Postoperatively, more women than men developed PUs, and female sex was one risk factor identified in multiple stepwise regression analyses.25 One reason for the sex difference may be attributed to soft tissue quality; that is, body composition, such as tissue mass and area, frequently differs between men and women. Generally, men are taller and heavier than women. Body muscle percentage, leg bone-free lean mass, calf muscle cross-sectional area, and calf muscle density are greater in men than in women, whereas the opposite is true for body fat percentage, leg fat mass, calf fat cross-sectional area, and calf fat density.26

Body mass index

In the present study, there were no significant differences associated with the participants’ weight or BMI for the total force or the four types of EP. A study reported that BMI was not significant in ICU patients with PUs.27

However, weight and BMI are widely considered to be predictive factors of supine position-related PU development. Unadjusted analyses have revealed statistically significant associations between BMI and the incidence of hospital-acquired PUs.23 In multivariate analyses, BMI was associated with the presence of hospital-acquired PUs.24 In logistic regression, morbid obesity (BMI ≥40 kg/m2) was associated with PUs in critically injured blunt trauma patients.28

Conversely, being underweight was a significant and distinct factor in PU development in a neurologic ICU.7 The postoperative patients who developed PUs weighed significantly less and had a lower BMI.25 Thin patients were at higher risk of PUs in the sacral region than those with normal weight and obese patients.29 Individuals who were underweight had a higher risk of developing PUs in nursing home.30 According to logistic regression analysis, low BMI was a significant predictor of PUs in hospital settings.22

An international PU prevalence survey showed that there was a higher prevalence of PUs in patients with low BMI and in those with low or high body weight; furthermore, one in ten patients with PUs was extremely obese.8 It has been reported that the incidence of PUs in intensive care patients who were underweight, normal weight, obese, and extremely obese was 8.6%, 5.5%, 2.8%, and 9.9%, respectively.31

In the present study, the mean BMI was 21.4±3.0 kg/m2 with limited variation. It may be clear that the more an individual weighs, the greater the force that would be exerted; however, whether the peak area would increase enough to compensate for an increase in pressure seems unlikely. Future studies should investigate the relationship between PUs and a large range of BMI, including underweight and overweight participants, using curve-fitting with various functions. This relationship remains to be proven by future research; such research would help quantify the potential risk associated with metabolic disorders in slim and obese individuals.

Position

Different positions, such as the supine and lithotomy positions, may result in different contact areas and external loading at various body locations. Muscle and fat tissue loading at the sacral region under bony prominences in the lithotomy position will be substantially greater than that when the patient is lying down. For some immobile patients, the onset of PUs is likely to occur sooner when maintaining a sitting posture than when lying down.

In the operating room, the patient’s body is generally placed on a specific soft mattress spread over the flat electric operating table. The probability of developing PUs is dependent on the pad and operating table mattress.32 The mattress is useful for patients who are at moderate to high risk of developing PUs. Some pressure-redistribution overlays significantly decrease the postoperative incidence of PUs in surgical patients.6 EP to the sacral region in the lithotomy position is reduced by the decrease in loading from using the KCLH system. Therefore, sex and weight differences in the EP at a body location may depend on the contact area and external loading.

Study limitations

This study has some limitations. First, we selected BP, PBP, CP, and PCP as representative EPs when using the BIG-MAT system, but we were unable to gather clear evidence on the correlations between these EPs and the actual perfusion pressure within the capillary vessels. Therefore, in future, we will need to obtain additional data on the correlations between perfusion pressure and the EPs measured using the BIG-MAT system.

Second, some cases of PUs occur with operations under general anesthesia. General anesthetics lower blood pressure, that is, cause hypotension, which may compromise perfusion in loaded tissues; patients undergoing prolonged surgeries are considered at a high risk of developing PUs. When a patient is conscious, prolonged time spent in a specific position that causes skin and muscle compression gradually results in discomfort. Under anesthesia, patients are unconscious, do not experience discomfort, and are unable to control their position. Therefore, we should measure EPs in participants with the use of sedation, analgesia, and muscle relaxant.

Third, risk factors of PU development are protein–calorie malnutrition, skin wetness caused by sweating or incontinence, diseases such as arteriosclerosis that reduce blood flow to the skin, or diseases that reduce sensation in the skin, such as paralysis or neuropathy. A report showed that the following risk factors may play a role in PU development in the ICU: fecal incontinence and diarrhea, low preoperative protein and albumin concentrations, disturbed sensory perception, moisture of the skin, impaired circulation, use of inotropic drugs, diabetes mellitus, the patient being too unstable to turn, decreased mobility, and high acute physiology and chronic health evaluation (APACHE) II score.33 Furthermore, reduced mobility, urinary incontinence, cognitive impairment, low serum albumin, and length of stay,20 and infection, age, length of stay, and total Braden score were significantly associated with the presence of PUs,21 and older age, Caucasian race, and lower Braden Scale scores were predictors of PUs.19 Patients aged 65 years and older were at the highest risk.2 Scores on the Braden Scale at the time of admission, number of vasopressors, occurrence of multiple surgeries during admission, and risk of mortality were significant predictors of PUs in hospital settings.22 The Braden Scale is composed of six broad clinical categories: sensory perception, moisture, activity, mobility, nutrition, and friction and shear, with a score of 18 or less indicating an increased risk of developing PUs.1 These physiologic and pathologic risk factors place the patients at risk because of impairment of the microcirculatory system. In the present study, the participants were young, healthy adult volunteers with limited BMI. Future studies should include participants who have not only wide ranges of age and BMI, but also pathologic conditions associated with increased risks of reduced blood flow and PU development in the sacral region during surgeries.

Fourth, the duration of surgery is a risk factor for the development of PUs.22,33 PUs in subdermal tissues under bony prominences are very likely to occur between the first hour and 4–6 hours after sustained loading.34 PUs can also occur within 2–6 hours. The median operative time for patients developing PUs was 4.4835 and 4.6 hours.6 Combined with a prolonged surgical time, the lithotomy position may cause PUs. The duration of surgery should, therefore, be as short as possible. In future, we should measure EPs in participants over a long period.

Finally, because the BIG-MAT system is not currently approved for clinical use as a medical instrument, it can only be used in clinical studies with the approval of the relevant ethics committees.

Conclusion

Using the BIG-MAT system, we measured four types of EP on the sacral region for participants lying in the lithotomy position. There were no sex-related differences in the EPs, or any significant correlations between the EPs and the participants’ height, weight, or BMI. Thus, patients’ height, weight, and BMI may not contribute to their risk of developing lithotomy position-related PUs in the sacral region. The noninvasive pressure distribution measurement system BIG-MAT for patients in the lithotomy position during operation could become a significant device to estimate EP at the sacral region.

Acknowledgment

The authors thank the students of Okayama Prefectural University who participated as volunteers in this study.

Disclosure

The authors report no conflicts of interest in this work.


References

1.

Lyder CH. Pressure ulcer prevention and management. JAMA. 2003;289(2):223–226.

2.

Kröger K, Niebel W, Maier I, Stausberg J, Gerber V, Schwarzkopf A. Prevalence of pressure ulcers in hospitalized patients in Germany in 2005: data from the Federal Statistical Office. Gerontology. 2009;55(3):281–287.

3.

Groeneveld A, Anderson M, Allen S, et al. The prevalence of pressure ulcers in a tertiary care pediatric and adult hospital. J Wound Ostomy Continence Nurs. 2004;31(3):108–120.

4.

Meehan M. National pressure ulcer prevalence survey. Adv Wound Care. 1994;7(3):27–30, 34, 36–38.

5.

Stotts NA. Risk of pressure ulcer development in surgical patients: a review of the literature. Adv Wound Care. 1999;12(3):127–136.

6.

Pham B, Teague L, Mahoney J, et al. Support surfaces for intraoperative prevention of pressure ulcers in patients undergoing surgery: a cost-effectiveness analysis. Surgery. 2011;150(1):122–132.

7.

Fife C, Otto G, Capsuto EG, et al. Incidence of pressure ulcers in a neurologic intensive care unit. Crit Care Med. 2001;29(2):283–290.

8.

VanGilder C, MacFarlane G, Meyer S, Lachenbruch C. Body mass index, weight, and pressure ulcer prevalence: an analysis of the 2006–2007 International Pressure Ulcer Prevalence Surveys. J Nurs Care Qual. 2009;24(2):127–135.

9.

Baugh N, Zuelzer H, Meador J, Blankenship J. Wound wise: wounds in surgical patients who are obese. Am J Nurs. 2007;107(6):40–50.

10.

Sato S, Mizuma M, Kawate N, Kasai F, Watanabe H. Evaluation of sit-to-stand motion using a pressure distribution measurement system – effect of differences in seat hardness on sit-to-stand motion. Disabil Rehabil Assist Technol. 2011;6(4):290–298.

11.

Mizuno J, Namba C, Takahashi T. Measurement of external pressure of peroneal nerve tract coming in contact with lithotomy leg holders using pressure distribution measurement system BIG-MAT®. Masui. 2014;63(10):1167–1171.

12.

Mizuno J, Takahashi T. Factors that increase external pressure to the fibular head region, but not medial region, during use of a knee-crutch/leg-holder system in the lithotomy position. Ther Clin Risk Manag. 2015;11:255–261.

13.

Mizuno J, Takahashi T. Male sex, height, weight, and body mass index can increase external pressure to calf region using knee-crutch-type leg holder system in lithotomy position. Ther Clin Risk Manag. 2016;12:305–312.

14.

Lee JW, Cassorla L. Lithotomy, specific positions, patient positioning and associated risks. In: Miller RD, Pardo MC Jr, editors. Basics of Anesthesia. 6th ed. Philadelphia: Elsevier Saunders; 2011:304–305.

15.

Landis EM. Micro-injection studies of capillary blood pressure in human skin. Heart. 1930;15:209–228.

16.

Hargens AR, Akeson WH, Mubarak SJ, et al. Fluid balance within the canine anterolateral compartment and its relationship to compartment syndromes. J Bone Joint Surg Am. 1978;60(4):499–505.

17.

Krouskop TA, Garber SL. Interface pressure measurements. J Enterostomal Ther. 1990;17(4):182.

18.

Allen V, Ryan DW, Murray A. Measurements of interface pressure between body sites and the surfaces of four specialised air mattresses. Br J Clin Pract. 1994;48(3):125–129.

19.

Bergstrom N, Braden B, Kemp M, Champagne M, Ruby E. Multi-site study of incidence of pressure ulcers and the relationship between risk level, demographic characteristics, diagnoses, and prescription of preventive interventions. J Am Geriatr Soc. 1996;44(1):22–30.

20.

Gallagher P, Barry P, Hartigan I, McCluskey P, O’Connor K, O’Connor M. Prevalence of pressure ulcers in three university teaching hospitals in Ireland. J Tissue Viability. 2008;17(4):103–109.

21.

Bours GJ, De Laat E, Halfens RJ, Lubbers M. Prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units. Results of a cross-sectional survey. Intensive Care Med. 2001;27(10):1599–1605.

22.

Tschannen D, Bates O, Talsma A, Guo Y. Patient-specific and surgical characteristics in the development of pressure ulcers. Am J Crit Care. 2012;21(2):116–125.

23.

Gardiner JC, Reed PL, Bonner JD, Haggerty DK, Hale DG. Incidence of hospital-acquired pressure ulcers – a population-based cohort study. Int Wound J. 2016;13(5):809–820.

24.

Corniello AL, Moyse T, Bates J, Karafa M, Hollis C, Albert NM. Predictors of pressure ulcer development in patients with vascular disease. J Vasc Nurs. 2014;32(2):55–62.

25.

Lindgren M, Unosson M, Krantz AM, Ek AC. Pressure ulcer risk factors in patients undergoing surgery. J Adv Nurs. 2005;50(6):605–612.

26.

Sherk VD, Thiebaud RS, Chen Z, Karabulut M, Kim SJ, Bemben DA. Associations between pQCT-based fat and muscle area and density and DXA-based total and leg soft tissue mass in healthy women and men. J Musculoskelet Neuronal Interact. 2014;14(4):411–417.

27.

Terekeci H, Kucukardali Y, Top C, Onem Y, Celik S, Oktenli C. Risk assessment study of the pressure ulcers in intensive care unit patients. Eur J Intern Med. 2009;20(4):394–397.

28.

Newell MA, Bard MR, Goettler CE, et al. Body mass index and outcomes in critically injured blunt trauma patients: weighing the impact. J Am Coll Surg. 2007;204(5):1056–1061.

29.

Kottner J, Gefen A, Lahmann N. Weight and pressure ulcer occurrence: a secondary data analysis. Int J Nurs Stud. 2011;48(11):1339–1348.

30.

Akca NK, Aydin G, Gümüs K. Pressure ulcers and their associated factors in nursing home inmates. J Coll Physicians Surg Pak. 2015;25(1):27–30.

31.

Hyun S, Li X, Vermillion B, et al. Body mass index and pressure ulcers: improved predictability of pressure ulcers in intensive care patients. Am J Crit Care. 2014;23(6):494–500.

32.

Nixon J, McElvenny D, Mason S, Brown J, Bond S. A sequential randomised controlled trial comparing a dry visco-elastic polymer pad and standard operating table mattress in the prevention of post-operative pressure sores. Int J Nurs Stud. 1998;35(4):193–203.

33.

Keller BP, Wille J, van Ramshorst B, van der Werken C. Pressure ulcers in intensive care patients: a review of risks and prevention. Intensive Care Med. 2002;28(10):1379–1388.

34.

Gefen A. How much time does it take to get a pressure ulcer? Integrated evidence from human, animal, and in vitro studies. Ostomy Wound Manage. 2008;54(10):26–28, 30–35.

35.

Aronovitch SA. Intraoperatively acquired pressure ulcers: are there common risk factors? Ostomy Wound Manage. 2007;53(2):57–69.

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