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Epidemiology, diagnosis, and management of atrial fibrillation in women

Authors Poli D, Antonucci E

Received 15 January 2015

Accepted for publication 5 March 2015

Published 11 June 2015 Volume 2015:7 Pages 605—614


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 5

Editor who approved publication: Professor Elie Al-Chaer

Video abstract presented by Daniela Poli.

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Daniela Poli,1 Emilia Antonucci2

1Thrombosis Centre, Department of Heart and Vessels, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy; 2Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

Abstract: Atrial fibrillation (AF) is the most common arrhythmia and has become a serious public health problem. Moreover, epidemiological data demonstrate that incidence and prevalence of AF are increasing. Several differences in epidemiological patterns, clinical manifestations, and incidence of stroke have been reported between AF in women and in men, particularly in elderly women. Elderly women have higher blood pressure than men and a higher prevalence of heart failure with preserved ejection fraction, both independent risk factors for stroke. On the basis of the evidence on the higher stroke risk among AF in women, recently, female sex has been accepted as a risk factor for stroke and adopted to stratify patients, especially if they are not at high risk for stroke. This review focuses on available evidence on sex differences in AF patients, and examines factors contributing to different stroke risk, diagnosis, and prognosis of arrhythmia in women, with the aim to provide an analysis of the available evidence.

Keywords: anticoagulants, bleeding, hypertension, stroke

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