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Dementia Diagnoses and Treatment in Geriatric Ward Patients: A Cross-Sectional Study in Poland

Authors Wojszel ZB

Received 16 September 2020

Accepted for publication 17 October 2020

Published 13 November 2020 Volume 2020:15 Pages 2183—2194


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Richard Walker

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Zyta Beata Wojszel1,2

1Department of Geriatrics, Medical University of Bialystok, Bialystok, Poland; 2Department of Geriatrics, Hospital of the Ministry of Interior in Bialystok, Bialystok, Poland

Correspondence: Zyta Beata Wojszel
Department of Geriatrics, Medical University of Bialystok, Fabryczna Str. 27, Bialystok 15-471, Poland
Tel +48 85 869 4982
Email [email protected]

Purpose: The study aimed to determine the prevalence of dementia, its types, and treatment in geriatric ward patients.
Patients and Methods: A cross-sectional study of 406 patients (77.8% women, median age 82, IQR (77– 86) years) who underwent a comprehensive geriatric assessment in one of the Polish hospitals between September 2014 and April 2015 was conducted.
Results: Dementia was diagnosed in 132 (32.5%) patients (46% mixed dementia; 32% Alzheimer’s disease; 10%vascular dementia; 5% dementia in Parkinson’s disease; 4% frontotemporal; 3% atypical parkinsonism). A total of 95 (72%) dementia cases were not detected before, and in the above half of these patients, it was not mentioned in the referral document. Only 33.3% of dementia patients were on cognitive enhancers (donepezil, rivastigmine, or memantine); 36.4% received antipsychotics, 45.5% received anti-depressants, 25.8% received nootropics, and 16.7% received anxiolytics/hypnotics.
Discussion: The results confirmed the high incidence of underdiagnoses and undertreatment of dementia in patients admitted to the geriatric ward. It is partly due to the lack of systematic cognitive assessment in primary care settings, although other factors can play a role.

Keywords: comprehensive geriatric assessment, geriatric ward, dementia diagnosis, dementia treatment, anti-dementia medications, cognitive enhancers, psychotropic medications, antipsychotics, anti-depressants, underdiagnoses, undertreatment


  • There is no reliable data on the prevalence and treatment of dementia in the population of older people burdened with chronic diseases and disability in Poland.
  • This cross-sectional study of 406 older patients admitted to the geriatric ward found a 32% prevalence of dementia, and only one-third was detected before admission and treated. High use of neuroleptics and anti-depressants was found, significantly higher in previously diagnosed dementia.
  • Research on a representative sample of community-dwelling older people is needed to evaluate the situation of dementia diagnosis and treatment in Poland.


Dementia is one of the most common psychogeriatric syndromes associated with significant morbidity and mortality,1,2 and nursing home placement risk.3 Due to the aging of the population, the disease burden of dementia in developed countries is still growing, as age is one of the main risk factors of cognitive deterioration. It is projected that in the next decades, the number of persons suffering from dementia will rise considerably in many developed and developing countries.4–7 In many countries, there is still the problem of late detection of dementia and too little appropriate therapy implementation.8–12 Although no systematic screening for dementia in the general population is recommended,13 it is emphasized, that assessing cognitive performance ought to be the inherent part of a comprehensive geriatric assessment.14 Some studies support the diagnosis of dementia in very elderly patients with multiple comorbidities, as influencing their prognosis and quality of life.11,15,16

There is no reliable data on the prevalence and incidence of dementia in the Polish population. In the last nationwide multidisciplinary study on aging in Poland – the PolSenior study carried out in 2008–2012 – some attention was paid to the prevalence of cognitive deterioration in the community-dwelling older people.17,18 Cognitive abilities in the representative sample of people aged 65+ years were estimated in this project based on the Mini-Mental State Examination (MMSE). Only 31.6% of the studied sample had the MMSE score above 27 points; in 36.3% of the cases, the score was within the range of 24–27 points (treated as mild cognitive impairment), and 38% of participants had the score below 24 points – suggestive for dementia. Unfortunately, no attempt was made in the PolSenior study to provide an in-depth and reliable assessment of the prevalence of dementia, its causes, and treatment. Nevertheless, the study revealed that the use of cognitive enhancers in Poland's elderly population is negligible. That could be the result of either too rare diagnosing dementia by doctors or a consequence of the high cost of anti-dementia therapy in this period. Earlier research, carried out over 20 years ago by Gabryelewicz and co-workers (based on a questionnaire screening and more in-depth cognitive assessment), revealed quite similar dementia rates in Warsaw to those found in other European studies.19 However, in these times, there was little awareness of the issue of dementia in Poland and virtually no access to anti-dementia medicatons.

There was no research carried out and recently published that could provide information on how the situation looks like nowadays in Poland – not only on the prevalence of dementia but also on its diagnosis and treatment. The study presented in this paper attempts to – at least partially – fill this gap. The aim of this study, conducted among patients aged 60+ hospitalized in one of the geriatric wards in Poland, was to determine the prevalence of dementia and its types, the treatment with anti-dementia drugs at admittance and discharge from the ward, and the usage of other psychotropic medications in a population highly burdened with co-morbidity and disability.

Patients and Methods

Research Site

The geriatrics ward is located in a 159-bed hospital – one of the four multidisciplinary hospitals in Bialystok. The Department of Geriatrics of the Medical University of Bialystok is located here. It has 17 beds and provides care to inhabitants of rural and urban areas of the Podlaskie region in north-eastern Poland, one of the demographically oldest Polish provinces. Bialystok city, with above 300 000 inhabitants, is its capital.

The department of geriatrics is a subacute ward. Older people with multimorbidity and physical and/or cognitive disabilities are admitted mainly in a planned manner. The average waiting time for admission to the ward is approximately 3 months. A comprehensive geriatric assessment by the multidisciplinary team is performed during the patients’ hospital stay. It aimes to identify reasons for patients’ functional decline, diagnose geriatric syndromes, and reduce polypharmacy.


A total of 416 consecutive patients admitted to the ward between September 2014 and April 2015 were included in the analysis but due to the limited availability of detailed data on pharmacotherapy before admittance in 10 cases, the final analysis was carried out in 406 patients. It was a secondary analysis of data collected during the cross-sectional study on frailty and multimorbidity in patients of the Department of Geriatrics (Hospital of the Ministry of Interior and Administration in Bialystok, Poland).20 Patients' enrollment to the study groups is presented on Figure 1.

Figure 1 Patients’ enrolment to the study.

Measures and Procedure

The data were collected retrospectively based on patients’ paper and electronic hospital health records. Data collected included information on patient’s age, gender, place of residence (urban/rural; community-dwelling/nursing home), way of living (alone/with others), years of education, history of hospitalizations in the previous year, the prevalence of 14 chronic diseases (atrial fibrillation, chronic arthritis, chronic cardiac failure, chronic obstructive pulmonary disease, chronic renal disease, diabetes/prediabetes, hypertension, ischemic heart disease, myocardial infarction, neoplasm, osteoporosis, parkinsonism, peripheral arterial disease, and stroke), and medications taken before hospitalization. Five or more drugs taken were treated as “polypharmacy”, and five or more diseases of 14 listed – as “multimorbidity”. The main reason for the referral to the geriatric ward (according to the ICD 10 classification) was extracted from the referral document, and information on hospital length of stay was gathered.

Patients diagnosed with dementia at discharge were classified as the dementia group and the rest of the participants as the non-dementia group. The assessment process for dementia at the geriatrics department includes a few consecutive steps. It starts with cognitive screening with the Abbreviated Mental Test Score (AMTS) in all patients admitted to the department.21 In subjects with an abnormal AMTS result or with memory complaints, or with behavioral disturbances history collected from the patient’s caregiver, assessment with MMSE is performed.22 Additionally to the row result of the MMSE, a score adjusted for age and years of education, according to Mungas and co-corkers’ correction, is calculated.23 The in-depth neuropsychological evaluation is performed only if a patient is referred with suspected dementia, when the patient and/or their caregivers report memory problems and behavioral disorders or when the result of the cognitive screening tests performed on admission is abnormal. In some cases, this diagnosis is postponed (patients with depression, delirium). Dementia was classified into six subtypes based on the international criteria: Alzheimer’s disease (AD); vascular dementia (VaD); mixed dementia of AD and VaD (MD); frontotemporal dementia (FTD); dementia associated with Parkinson’s disease (PDD); and dementia in atypical parkinsonism (APD).24,25

The results of comprehensive geriatric assessment taken into account in the analysis included the ability to perform activities of daily living (ADL) assessed with the Barthel Index,26 6 instrumental ADL items of Duke OARS scale (IADL),27 and frailty status evaluation with the seven items Canadian Study of Health and Aging Clinical Frailty Scale (CFS);28 the score of 6 or 7 of CFS was classified as severe frailty.

Psychotropic medications received by the patient before admittance were categorized according to the Anatomical Therapeutic Chemical (ATC) Classification System: antipsychotics (N05A), anxiolytics (N05B), hypnotics/sedatives (N05C), anti-depressants (N06A), anticonvulsants (N03), anti-dementia drugs (N06D), and anti-vertigo (N07).29,30 Additionally, information on taking peripheral vasodilators and lipid modifying agents was also gathered. For anti-dementia medications, also information on prescription at discharge was collected.

Data Analysis

Analyses were done with IBM SPSS Version 18 Software suit (SPSS, Chicago, IL, USA). The variables’ distribution was checked with Shapiro–Wilk tests. They were presented as frequency and percentage (categorical variables), as means and standard deviation (normally distributed quantitative variables), or as medians and interquartile range (not normally distributed quantitative variables). Proportions were compared using χ2 tests, while the Student’s t-test for independent samples and Mann–Whitney U-test were used to compare means and medians. Relative risks (RRs) with confidence intervals (CIs) were calculated to evaluate the potential risk factors that might influence the occurrence of dementia in geriatric in-patients. Differences between two dependent samples were assessed with Wilcoxon signed-rank test. In all analyses, a two-tailed P value of less than 0.05 was regarded as significant. Analyses did not include missing data.

Ethics Approval

The source study was approved by the Ethics Committee at the Medical University of Bialystok (no R-I-002/305/2013). All procedures performed in the study were in accordance with the ethical standards of the Medical University of Bialystok research committee and with the Helsinki declaration and its later amendments. The study can be classified as a study of “usual practice”. All study participants gave their informed consent to participate in it. Secondary analysis of data did not require additional approval.


Demographics and Clinical Characteristics

Demographics and clinical characteristics of the study group are presented in Table 1. The median age in the study group was 82 (IQR, 77–86) years. Most of the participants were at the age of 75 or more (84.2%), female (77.8%), living in the urban area (78.8%), community-dwelling (96.8%), and living with others (70.3%). More than half of them did not complete primary school. The study group was highly burdened with multimorbidity and polypharmacy. Hypertension, ischemic heart disease, chronic cardiac failure, atrial fibrillation, diabetes, chronic osteoarthritis, and chronic kidney disease were especially common.

Table 1 Demographics and Clinical Characteristics of Sample

Diseases of the circulatory system (34%), mental and behavioural disorders (22.2%), and diseases of the musculoskeletal system and connective tissue (11.1%) were the most frequent causes of the referral to the geriatric department. Dementia as the main ICD-10 diagnosis was the cause of the referral in 18.5% of the hospitalized patient (47.7% diagnosed with dementia and 4.4% of non-dementia patients). In patients for which dementia was not confirmed, the alternative diagnoses at discharge included depression combined with the bad general health status (4 cases), depression (3 cases), diabetes/hypoglycemia (3 cases), and mild cognitive impairment (2 cases). The median of the hospital stay was 8 (IQR, 5–9) days, and did not differ between dementia and non-dementia group. The vast majority of patients (96.3%) were discharged home, 3 patients (0.7%) died, 8 (2%) were transferred to another hospital/ward for further treatment (eg, due to stroke or acute coronary syndrome), and 4 (1%) were transferred to a long-term care institution.

Dementia Diagnosis and Memory Complaints

Of the 406 subjects, 132 (32.5%) were dementia patients and the other 274 (67.5%) served as controls (Table 1). In 37 (28%) of dementia cases, the diagnosis of dementia was established before admission. In the next 60.6% of them, memory complaints or behavioral disturbances before hospitalization were confirmed in the history taken (contrary to 10.9% in non-dementia cases, P<0.001). In 2 cases of dementia diagnosed and treated before hospital stay, the diagnosis was finally excluded after the neuropsychologist’s assessment – an alternative diagnosis was depression, and anti-depressants were prescribed for these patients.

The most frequent dementia type was the MD, observed in 61 (45.9%) cases. AD was diagnosed in 43 (32.3%) cases and VaD in 13 (9.8%) cases. Less frequently PDD (n=7; 5.3%), APD (n= 4; 3.0%), and FTD (n=5; 3.8%) were observed (Figure 2).

Figure 2 Dementia types prevalence in geriatric ward patients.

Patients with dementia were significantly older, more frequently male, and less frequently living alone. As it was expected, they performed significantly worse in cognitive abilities testing (AMTS, row, and corrected MMSE). In 35 cases, AMTS was not available because patients’ health status did not allow them to perform testing. Dementia sufferers significantly more frequently were diagnosed with peripheral arterial disease, history of stroke/transient ischemic attack (TIA), and parkinsonism but significantly less frequently with chronic osteoarthritis and osteoporosis. There were no differences between dementia and non-dementia groups in the prevalence of hypertension, ischemic heart disease, myocardial infarction, chronic cardiac failure, atrial fibrillation, diabetes, neoplasm, COPD, and chronic kidney disease. The groups did not differ in the number of drugs taken before admission, the prevalence of polypharmacy, and hospitalizations in the last 12 months. Dementia patients were significantly more seriously dependent on others in personal and instrumental ADL and were more severely frail and significantly more frequently reported urinary and fecal incontinence (Table 1).

Cognitive Abilities

As expected, patients with dementia differed significantly in the results achieved in the screening tests of cognitive abilities from patients without such diagnosis (Table 1). The median value of the AMTS score, the mean values of the MMSE, and the corrected MMSE scores were significantly lower in dementia sufferers.

In dementia patients, MMSE was performed in 95 cases – in 20 patients previously diagnosed and in 75 diagnosed during hospitalization. Both groups did not differ in the MMSE score (16.1±4.8 versus 16.89±4.6, respectively, P=0.50). In 86 dementia cases, the corrected result of the MMSE was available. In dementia previously diagnosed and diagnosed during hospital stay, the corrected scores were also similar (18.56±3.5 versus 20.2±3.8, P=0.11). A total of 50% diagnosed during the hospital stay patients had MMSE score <17 points and corrected MMSE score <20 points so dementia was diagnosed only in the moderate or the more severe phase. The reasons for missing MMSE in “dementia” group included: aphasia – 3 cases, advanced dementia in patients with very limited cognition – 11 cases, severe general health status not allowing for cognitive status assessment – 5 cases, patients with dementia previously diagnosed and not re-assessed during a hospital stay – 17 cases, and unknown reason – 1 case. It is also worth mentioning that the MMSE score did not differ significantly between patients referred to the hospital with the ICD 10 code of dementia and those without such a diagnosis in the referral letter (Figure 3).

Figure 3 MMSE results depending on the previous diagnosis and ICD-10 code of dementia on referral documents.

Anti-Dementia Treatment

Only one-third of dementia patients received cognitive enhancers before hospitalization (Table 2). The most common was cholinesterase inhibitor (ChE-I), used in 29.5% of dementia cases. Memantine- N-methyl-D-aspartate (NMDA) receptor antagonist was reported less frequently. It was used as a single anti-dementia agent or in combination with ChE-I. The percentage of dementia cases treated with any anti-dementia medication increased significantly to 74.0%, mainly due to the significant increase in a prescription for ChE-I. Incorrect diagnosis of dementia was verified in two cases, which resulted in cognitive enhancers discontinuation.

Table 2 Anti-Dementia Medications (N06D) at Admittance and at Discharge from the Department

Other Psychotropic Medications Taken Before Hospitalization

Patients who were diagnosed with dementia were significantly more often on anti-depressants at admission (45.5% versus 29.6% in the non-dementia group, P=0.002) - Table 3. Selective serotonin/serotonin-noradrenalin reuptake inhibitors were the most frequently used anti-depressants in the whole study group, and they were significantly more often prescribed to dementia patients. Mianserin or other groups of anti-depressants were used less often. Dementia patients significantly more often than the non-dementia group were on antipsychotics at admission (36.4% versus 7.3% in the non-dementia group, P<0.001), and quetiapine was the most frequently used neuroleptic. Haloperidol, promazine, risperidone, sulpiride, or other antipsychotic medications were used less frequently, and the first two were used significantly more often in dementia sufferers. In 6 cases (1.4%), two or three different neuroleptics were used simultaneously. In the case of patients with dementia, those diagnosed before admission to the hospital were significantly more likely to be on anti-depressants and neuroleptics (64.9% versus 37.9%, P = 0.006; and 54.1% versus 29.5%, P = 0.02, respectively; Figure 4). Nevertheless, these data suggest that about a third of dementia cases were overlooked by their regular doctors and treated as depression or psychosis. There were no significant differences observed in the use of anxiolytics/hypnotics, anticonvulsants, psychostimulants/nootropics, and antivertigo medications.

Table 3 Psychotropic Medications at Admittance to the Department

Figure 4 Use of different groups of psychotropic medications in demented patients (detected and undetected before hospitalization).


In the present study, 1/3 of the people hospitalized in the geriatric ward were diagnosed with dementia. This frequency was much higher than in the earlier studies conducted in the community-dwelling older people in Poland or other countries.19,31–33 In Gabrylewicz et al’s study, age-specific prevalence of dementia in the age-groups 65–69, 70–74, 75–79, 80–84 was 1.9%, 5.8%, 8.6%, and 16.5%, respectively.19 Dementia prevalence in the geriatric ward was rather very similar to those observed in more disabled populations, with similar characteristics to the cohort of older people described in this study (in receipt of formal home care in North Dublin,34 or in nursing home residents in Germany).35 One of the reasons could be that the need for cognitive dysfunction assessment is one of the causes for referral to the geriatric ward in some cases, as it was shown in the current study. Whereas by the National Health Fund in Poland guidelines, people over 60 can be treated in the geriatric ward, the majority of hospitalized patients were over 75 years of age. The criterion of referral to this ward is not the calendar age itself, but the specificity of patients’ health problems. Most of them are people with multiple chronic diseases, polypharmacy, and a high prevalence of geriatric syndromes (including dementia). More advanced age is a crucial risk factor for these. Contrary to other studies, men were considerably more often dementia sufferers. One of the potential explanations could be the high prevalence of Parkinson’s disease and parkinsonism in the study group, as some studies confirmed that male sex was a predictor of cognitive decline in parkinsonian patients.36

In contrast to the other studies' results, suggesting that Alzheimer’s disease is the most common cause of dementia,37 this type of dementia was only the second most common type in the current study, after the mixed one, observed in 46% of cases. It could be explained at least partially by the participants’ health profiles. They were burdened with cardiovascular disorders, diabetes, and chronic kidney disease. A history of cerebral stroke – a well-known risk factor for cognitive decline – was reported in people with dementia twice as often as in the control group, and Parkinson’s disease/syndrome was three times more frequent than in the control group. On the other hand, studies carried out in recent years indicated that in most cases of dementia we dealt with overlapping of primary degenerative pathology and vascular background,38 and vascular cognitive impairment is a common contributor to cognitive impairment in later life.39 Moreover, the results of some studies have shown that the lack of neuroimaging assessment might lead to clinical overdiagnosis of Alzheimer’s disease and the underdiagnoses of vascular pathology.40 Every patient diagnosed with dementia had a CT scan, which may have also contributed to such results.

The study confirmed that as many as 72% of older adults living with dementia were not formally diagnosed before admission and – as a consequence – did not receive any anti-dementia medications. Memory problems or behavioral disturbances were observed in 82.4% of them and 50% of them had moderate cognitive deterioration. However, only in 47.4% of these cases dementia was suspected by a doctor referring the patient to the geriatric department. Thus, for 50 patients (37.9% of dementia cases), the treating physicians were unaware of the problem, although the MMSE score in these patients was similar to the observed in diagnosed cases. Similar results were achieved in elderly patients admitted to a post-acute rehabilitation facility in Lausanne, Switzerland.37 Not diagnosing dementia or detecting dementia in its later stage is raised in the literature.8,10–12 It can be due to various reasons.11 One-third of the people admitted to the ward lived alone. It was significantly less common in people with dementia, although the percentage of people living alone in this group was still high and amounted to 22.7% in the current study. In the case of infrequent or superficial contacts with family members, this may delay making the correct diagnosis. As confirmed in some studies, people with undiagnosed dementia tend to visit the doctor without an accompanying person, making it impossible to interview an independent informant.11 They may also be concerned about disclosing their diagnosis as it can affect their whole life and the attitude of their family and others.41 Assessment of cognitive functions in elderly patients – although recommended by geriatricians – has not entered the daily practice of family doctors in Poland, and international guidelines do not recommend universal screening for dementia.42 Hence, most cases of dementia are diagnosed only in their moderate phase, when behavioral disturbances attract the attention of people from the patient’s environment.43 It can have important implications both for patients and for their families connected with risks and complications of cognitive disability.15,16,44 The study results  suggest the need to address the problem of dementia in public media or through healthcare campaigns, as part of a more global dementia action plan.7,45 This could raise dementia awareness and reduce dementia stigma in Poland.

Limited financial availability of anti-dementia drugs can also influence dementia treatment. In Poland, partial, 70% reimbursement of pharmacotherapy costs in the study period covered only drugs from the ChE-I group. The patient bore the full cost of the memantine treatment. It could have contributed to the fact that it was used relatively rarely in this group. In 2017, the Ministry of Health launched the “Medications for 75“ project in Poland. ChE-I found a place on the reimbursement lists that included prescription drugs for people over 75, free of charge; unfortunately, memantine remained a non-reimbursed drug. Although the change should influence dementia treatment in Poland, awareness of the importance of cognitive assessment in geriatric patients seems to be the prevailing factor. The propensity to perform such an assessment depends on financial incentives for family doctors.12 The diagnosed type of dementia is another factor that can influence the treatment with cognitive enhancers. In AD, ChE-Is and memantine are recommended. They may also be considered for the treatment of vascular cognitive impairment and in selected parkinsonian patients.13,46 But in Poland, donepezil treatment is reimbursed only in AD, Lewy Body dementia, and PDD, whereas rivastigmine is reimbursed only in AD. Finally, it should also be taken into account that drugs used in dementia have no causal effect but act only symptomatically. Their effectiveness is limited, may change over time, or side effects may prevent their use in some patients.13 This can also affect their prescribing, and high rates of non-persistence in dementia patients who received a prescription for cognitive enhancers. Research carried out in Germany, for example, showed that only 69.9% of patients aged >70 who received a prescription for anti-dementia medication were on it six months after initiation of treatment, and only 56.2% after 12 months.47

The study confirmed other authors’ findings that different psychotropic drug use in patients with dementia remains high.48 Before admission to the department, they received anti-depressants and antipsychotics significantly more often than non-dementia patients. Both groups of medications were prescribed significantly more frequently in dementia detected before hospitalization. It may indicate that in the group of dementia earlier detected behavioral disorders and psychotic symptoms were more common. Maybe also physicians found it easier to prescribe psychotropic drugs when they knew that the patient had dementia. On the other hand, the results of different studies indicate depression and anxiety disorders as a possible cause or prodromal symptoms of dementia.49,50

The study results should be interpreted with caution as it has some limitations that should be mentioned. It was carried out not on a randomly selected representative sample of the older population but among patients hospitalized in the geriatrics department. Its results can be generalized only to similar patients groups, not to the general Polish older population. It was also based on a secondary analysis of data previously collected (during the routine geriatric evaluation of admitted patients- “usual practice” study). Therefore, data on some variables – such as MMSE scores – were not available for all patients, as indicated in Table 1.


In summary, dementia affects a significant percentage of patients in the geriatric ward. The majority of its cases are diagnosed only during a patient’s hospital stay. It is in part due to the lack of systematic cognitive assessment in primary care settings, although other factors can play a role.


The author appreciates very much the involvement of Dr. Agnieszka Kasiukiewicz in data collection and creating the database.


This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The source study was supported by the Medical University of Bialystok, grant number N/ST/ZB/15/001/3301. The financial sponsor played no role in the design, execution, analysis and interpretation of data.


The author reports no conflicts of interest for this work.


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