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Corpus callosum infarction with cognitive dysfunction: two case reports and literature review

Authors Zhang J, Tang Y, Sun Y, Xu Y, Pang L, Li J, Wu T, He M

Received 29 October 2017

Accepted for publication 3 January 2018

Published 13 February 2018 Volume 2018:14 Pages 511—515

DOI https://doi.org/10.2147/NDT.S155487

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Prof. Dr. Roumen Kirov

Peer reviewer comments 2

Editor who approved publication: Professor Wai Kwong Tang


Jianyu Zhang, Yi Tang, Yongan Sun, Yingda Xu, Lingen Pang, Jiaojiao Li, Taotao Wu, Mingli He

Department of Neurology, Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, Jiangsu, People’s Republic of China

Introduction: The incidence of corpus callosum infarction is low, and sudden cognitive dysfunction caused by corpus callosum infarction is very rare. We report two cases of acute corpus callosum infarction with sudden cognitive impairment, and the related basis, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of this disease are reviewed.
Cases presentation: The two patients had sudden and severe memory impairment and spatial orientation disorder. Their cognitive function scores were significantly lower, and their MRI demonstrated clear corpus callosum infarction. Through treatment, the symptoms improved significantly.
Discussion: This paper reports two cases with corpus callosum infarction with sudden cognitive impairment, and its relevant background is also reviewed, which will help doctors with the classification diagnosis of cerebral infarction and understanding of corpus callosum infarction.

Keywords: corpus callosum infarction, cognitive dysfunction, MRI, memory impairment, spatial orientation disorder

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