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Congenital nystagmus and negative electroretinography

Authors Roussi, Dalens H, Marcellier JJ, Bacin F

Published 6 April 2011 Volume 2011:5 Pages 429—434


Review by Single anonymous peer review

Peer reviewer comments 4

Mirella Roussi, Hélène Dalens, Jean Jacques Marcellier, Franck Bacin
Department of Ophthalmology, Clermont-Ferrand University, Clermont-Ferrand, France

Abstract: Congenital nystagmus is a pathologic oculomotor state appearing at about three to four months of age. The precise diagnosis requires detailed clinical examination and electrophysiological findings. This case report presents two male patients with congenital nystagmus examined longitudinally from the age of six months until 17-18 years of age. Clinical and electrophysiological protocols were detailed. The first results showed electronegative electroretinography in the two cases and examination combined with electroretinographic findings helped us to make the diagnosis of Congenital Night Stationary Blindness (CSNB). This diagnosis was confirmed by genetic studies. CSNB is interesting to study because through electrophysiological findings, it enables a better understanding of the physiology of neural transmission in the outer part of the retina.

Keywords: Congenital nystagmus, negative electroretinography, congenital night stationary blindness

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