Computer simulation of a novel pharmaceutical silicon nanocarrier
Saeed Soltani, Soroush Sardari, Sima Azadi Soror
Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
Abstract: We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.
Keywords: diatom, docking, artificial neural network, simulation, computerized methods
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