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Computer simulation of a novel pharmaceutical silicon nanocarrier

Authors Soltani S, Soroush Sardari S, Soror SA

Published 16 November 2010 Volume 2010:3 Pages 149—157

DOI https://doi.org/10.2147/NSA.S8378

Review by Single anonymous peer review

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Saeed Soltani, Soroush Sardari, Sima Azadi Soror
Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran

Abstract: We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.

Keywords: diatom, docking, artificial neural network, simulation, computerized methods

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