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Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study

Authors Kim KY, Miravitlles M, Sliwinski P, Costello R, Carter V, Tan J, Lapperre TS, Alcazar B, Gouder C, Esquinas C, García-Rivero JL, Kemppinen A, Tee A, Roman-Rodríguez M, Soler-Cataluña JJ, Price D, Rhee CK

Received 10 March 2019

Accepted for publication 5 June 2019

Published 25 July 2019 Volume 2019:14 Pages 1595—1601

DOI https://doi.org/10.2147/COPD.S208245

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Dr Richard Russell


Kyu Yean Kim,1 Marc Miravitlles,2,3 Pawel Sliwinski,4 Richard Costello,5 Victoria Carter,6,7 Jessica Tan,8 Therese Sophie Lapperre,8,9 Bernardino Alcazar,10 Caroline Gouder,11 Cristina Esquinas,2,12 Juan Luis García-Rivero,13 Anu Kemppinen,6 Augustine Tee,14 Miguel Roman-Rodríguez,15 Juan José Soler-Cataluña,3,16 David Price,6–7,17 Chin Kook Rhee1

1Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; 2Pneumology Department, University Hospital Vall d’Hebron/Vall d’Hebron Research Institute (VHIR), Barcelona, Spain; 3CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain; 42nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland; 5Department of Respiratory Medicine, Royal College of Surgeons, Dublin, Ireland; 6Optimum Patient Care, Cambridge, UK; 7Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 8Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark; 9Singhealth Duke-NUS Medical Academic Clinical Programme, Duke-NUS Medical School, Singapore; 10Respiratory Department, Hospital de Alta Resolución de Loja, Madrid, Spain; 11Department of Respiratory Medicine, Mater Dei Hospital, L-Imsida, Malta; 12Public Health, Mental, Maternal and Child Health Nursing Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain; 13Hospital Comarcal de Laredo, Cantabria, Spain; 14Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore; 15Primary Health-care Center Son Pisà, IB-Salut, Palma, Spain; 16Pneumology Department, Hospital Arnau de Vilanova, Valencia, Spain; 17Observational and Pragmatic Research Institute, Singapore

Abstract: We aimed to compare clinical characteristics between Asian and Western chronic obstructive pulmonary disease (COPD) patients. This was a sub-analysis of an international, multicenter, prospective cohort study. Asian patients were enrolled in Singapore and South Korea. Western patients were enrolled in Spain, Poland, Ireland, the United Kingdom, and Malta. A total of 349 patients were analyzed. Among them, 110 (32%) patients were Asian and 239 (68%) Western. Male sex was more predominant in Asian than in Western (95% versus 63%, respectively; P<0.01). Body mass index was significantly lower in Asian (23.5 versus 27.1; P<0.01). The proportion of patients with a history of exacerbation was lower in Asian (12% versus 64%; P<0.01). Although patients were enrolled by same inclusion criteria, there were several differences between Asian and Western COPD patients. Our study has shown unbiased real-world differences between Asian and Western COPD patients. Since prospective follow-up study is currently ongoing, the result of this study can be fundamental base of future analysis.

Keywords: COPD, Asian, Western


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