Clinical features and outcomes of tetanus: a retrospective study
Authors Fan Z, Zhao Y, Wang S, Zhang F, Zhuang C
Received 9 February 2019
Accepted for publication 29 March 2019
Published 16 May 2019 Volume 2019:12 Pages 1289—1293
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Cristina Weinberg
Peer reviewer comments 2
Editor who approved publication: Dr Joachim Wink
Zhe Fan,1,2,* Yue Zhao,3,* Shuang Wang,3 Feng Zhang,4 Chengjun Zhuang5
1Department of General Surgery, The Third People’s Hospital of Dalian, Dalian Medical University, Dalian, People’s Republic of China; 2Department of General Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of China; 3Graduate School, Dalian Medical University, Dalian, People’s Republic of China; 4Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, People’s Republic of China; 5Department of Critical Care Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, People’s Republic of China
*These authors contributed equally to this work
Background: Tetanus is a serious disease resulting in muscle spasm, and even death.
Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters.
Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71±9.05 years. Patient occupations included farming (47.0%), retired (23.5), homebound (23.5), and workers (6.0%). The causes of patient injuries were as follows: metal injury (52.9%), deep injury (29.4%), electrical injury (5.9%), maxillofacial region and knee injury (5.9%), and skin ulceration (5.9%). The disease duration ranged from 3 to 36 days, and the mean incubation period was 12.65±10.17 days. Four patients had co-morbidities. The infected patients were given tetanus antitoxin (TAT) and antibiotics treatment. One patient was given continuous renal replacement therapy (CRRT) and only one patient died.
Conclusions: In our department, although tetanus is a serious disease, with effective treatment, patients have reasonable cure and low death rates.
Keywords: tetanus, intensive care unit, retrospective study
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]